- claim_text
In sensory cortex, pyramidal neurons integrate bottom–up and top–down signals under the modulatory influence of key interneuron classes: parvalbumin (PV), somatostatin (SST), vasoactive intestinal peptide (VIP), and LAMP5-expressing neurogliaform cells each of which mediates distinct computational r
- raw_fields
{
"n": 0,
"doi": "10.1073/pnas.2504164122",
"claim": "In sensory cortex, pyramidal neurons integrate bottom–up and top–down signals under the modulatory influence of key interneuron classes: parvalbumin (PV), somatostatin (SST), vasoactive intestinal peptide (VIP), and LAMP5-expressing neurogliaform cells each of which mediates distinct computational r",
"title": null,
"cite_key": "Iqbal2025",
"evidence": "Reported in study using rat, cortex.",
"effect_size": null,
"text_access": "fulltext",
"study_system": "rat, cortex",
"_source_cluster": "cluster_10_species_disease",
"replication_status": "single study",
"_source_cluster_index": 51,
"claim_source_sentence": "In sensory cortex, pyramidal neurons integrate bottom–up and top–down signals under the modulatory influence of key interneuron classes: parvalbumin (PV), somatostatin (SST), vasoactive intestinal peptide (VIP), and LAMP5-expressing neurogliaform cells each of which mediates distinct computational roles including gain control, disinhibition, and normalization respectively ( 6 – 12 ).",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-733c0535ffcd"
]
- source_span
In sensory cortex, pyramidal neurons integrate bottom–up and top–down signals under the modulatory influence of key interneuron classes: parvalbumin (PV), somatostatin (SST), vasoactive intestinal peptide (VIP), and LAMP5-expressing neurogliaform cells each of which mediates distinct computational roles including gain control, disinhibition, and normalization respectively ( 6 – 12 ).
- evidence_refs
[
{
"ref": "paper:paper-733c0535ffcd"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}