Active behavior engages PV/SST/VIP interneurons via cholinergic inputs to enabl…

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scope: vip-interneurons
claim_text: Active behavior engages PV/SST/VIP interneurons via cholinergic inputs to enable context-dependent auditory cortex coding
section_id: section_08
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
review_repo: ComputationalReviewVIP
section_ref: wiki_page:computationalreviewvip-08-in-vivo-behavior
source_kind: review_finding
source_path: evidence/section_08_evidence_package.json
section_title: In Vivo Function During Behavior
review_bundle_ref: analysis_bundle:ab-2ce40c33e827
replication_status: unevaluated
review_package_ref: analysis_bundle:ab-2ce40c33e827
source_artifact_ref: wiki_page:computationalreviewvip-08-in-vivo-behavior
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
commit_sha: 95e761177f7d2ec565983d3307c14ec238f9677c
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP

Raw fields (5)

raw_fields

{
  "n": null,
  "doi": "10.1038/nn.4436",
  "pmid": "27798631",
  "tags": [
    "locomotion",
    "disinhibition",
    "optogen",
    "ach"
  ],
  "year": "2017",
  "claim": "Active behavior engages PV/SST/VIP interneurons via cholinergic inputs to enable context-dependent auditory cortex coding",
  "pmcid": "PMC5191967",
  "title": "Parallel processing by cortical inhibition enables context-dependent behavior.",
  "journal": "",
  "citation": "Kuchibhotla KV, Gill JV, Lindsay GW, Papadoyannis ES, Field RE, Sten TA, Miller KD, Froemke RC.",
  "cite_key": "Kuchibhotla2017",
  "effect_size": null,
  "text_access": "fulltext",
  "citedByCount": 318,
  "isOpenAccess": "Y",
  "evidence_type": "mechanism",
  "linked_topics": [
    "locomotion",
    "disinhibition",
    "ach",
    "optogen"
  ],
  "_source_cluster": "cluster_07_in_vivo_function",
  "relevance_score": 1,
  "replication_status": null,
  "_source_cluster_index": 3,
  "claim_source_sentence": "Whole-cell recordings showed that excitatory inputs were affected only modestly by context, but inhibition was more sensitive, with PV<sup>+</sup>, SOM<sup>+</sup>, and VIP<sup>+</sup> interneurons balancing inhibition and disinhibition within the network."
}

source_refs

[
  "paper:paper-73696115e165"
]

source_span

Whole-cell recordings showed that excitatory inputs were affected only modestly by context, but inhibition was more sensitive, with PV<sup>+</sup>, SOM<sup>+</sup>, and VIP<sup>+</sup> interneurons balancing inhibition and disinhibition within the network.

evidence_refs

[
  {
    "ref": "paper:paper-73696115e165"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

Active behavior engages PV/SST/VIP interneurons via cholinergic inputs to enabl…

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