Details

scope
vip-interneurons
claim_text
Locomotion increases activity of VIP, SST, and PV interneurons during visual stimulation in mouse V1, challenging a simple disinhibition model
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-08-in-vivo-behavior
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
section_title
In Vivo Function During Behavior
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
unevaluated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-08-in-vivo-behavior
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.7554/elife.14985",
  "pmid": "27552056",
  "tags": [
    "locomotion",
    "disinhibition",
    "gain_sst"
  ],
  "year": "2016",
  "claim": "Locomotion increases activity of VIP, SST, and PV interneurons during visual stimulation in mouse V1, challenging a simple disinhibition model",
  "pmcid": "PMC5030095",
  "title": "Behavioral-state modulation of inhibition is context-dependent and cell type specific in mouse visual cortex.",
  "journal": "",
  "citation": "Pakan JM, Lowe SC, Dylda E, Keemink SW, Currie SP, Coutts CA, Rochefort NL.",
  "cite_key": "Pakan2016",
  "effect_size": null,
  "text_access": "fulltext",
  "citedByCount": 218,
  "isOpenAccess": "Y",
  "evidence_type": "phenomenology",
  "linked_topics": [
    "locomotion",
    "disinhibition",
    "gain_sst"
  ],
  "_source_cluster": "cluster_07_in_vivo_function",
  "relevance_score": 0.9,
  "replication_status": null,
  "_source_cluster_index": 7,
  "claim_source_sentence": "Using in vivo two-photon calcium imaging in layers 2/3 and 4 in mouse V1, we reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model."
}
source_refs
[
  "paper:paper-acf576c0a2ed"
]
source_span
Using in vivo two-photon calcium imaging in layers 2/3 and 4 in mouse V1, we reveal that locomotion increases the activity of vasoactive intestinal peptide (VIP), somatostatin (SST) and parvalbumin (PV)-positive interneurons during visual stimulation, challenging the disinhibition model.
evidence_refs
[
  {
    "ref": "paper:paper-acf576c0a2ed"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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