Details
- scope
- mouse
- claim_text
- Introduction Orexin pathways are involved in multiple biological functions including sleep/wakefulness, metabolism, stress control, reward processes, and autonomic functions–.
- section_id
- section_09
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_09_evidence_package.json
- effect_size
- Effects on cataplexy-like episodes of (e) TAK-861 (0.3 and 1 mg/kg), (f) modafinil (30 and 100 mg/kg), and (g) clomipramine (15 and 50 mg/kg) for 3 h after administration in orexin-tTA;TetO DTA mice.
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-09
- source_kind
- review_finding
- source_path
- evidence/section_09_evidence_package.json
- source_span
- Introduction Orexin pathways are involved in multiple biological functions including sleep/wakefulness, metabolism, stress control, reward processes, and autonomic functions–.
- study_system
- mouse
- section_title
- The Hypothalamic Extension: Loops for Motivated Behavior
- evidence_summary
- fulltext_body
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-09
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_09_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/s41598-024-70594-1", "claim": "Introduction Orexin pathways are involved in multiple biological functions including sleep/wakefulness, metabolism, stress control, reward processes, and autonomic functions–.", "cite_key": "Mitsukawa2024", "evidence": "fulltext_body", "effect_size": "Effects on cataplexy-like episodes of (e) TAK-861 (0.3 and 1 mg/kg), (f) modafinil (30 and 100 mg/kg), and (g) clomipramine (15 and 50 mg/kg) for 3 h after administration in orexin-tTA;TetO DTA mice.", "text_access": "fulltext", "study_system": "mouse", "source_cluster_id": "cluster_08", "replication_status": "replication_unknown", "claim_source_sentence": "Introduction Orexin pathways are involved in multiple biological functions including sleep/wakefulness, metabolism, stress control, reward processes, and autonomic functions–.", "replication_evidence_dois": [], "effect_size_source_sentence": "Effects on cataplexy-like episodes of (e) TAK-861 (0.3 and 1 mg/kg), (f) modafinil (30 and 100 mg/kg), and (g) clomipramine (15 and 50 mg/kg) for 3 h after administration in orexin-tTA;TetO DTA mice." }- source_refs
[ "paper:paper-0035783a3b36" ]
- evidence_refs
[ { "ref": "paper:paper-0035783a3b36" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }