- claim_text
VIP-INs are upstream of the other observed neuron types 9 – 11 , 18 , and their hypoactivity in R6/2 mice could disinhibit SST-INs leading to their hyperactivity, which would in turn lead to increased inhibition of CSPNs explaining their hypoactivity.
- raw_fields
{
"n": 0,
"doi": "10.1101/2025.02.07.637155",
"claim": "VIP-INs are upstream of the other observed neuron types 9 – 11 , 18 , and their hypoactivity in R6/2 mice could disinhibit SST-INs leading to their hyperactivity, which would in turn lead to increased inhibition of CSPNs explaining their hypoactivity.",
"title": null,
"cite_key": "Blumenstock2025",
"evidence": "Reported in study using human, mouse, rat.",
"effect_size": null,
"text_access": "fulltext",
"study_system": "human, mouse, rat",
"_source_cluster": "cluster_10_species_disease",
"replication_status": "single study",
"_source_cluster_index": 115,
"claim_source_sentence": "VIP-INs are upstream of the other observed neuron types 9 – 11 , 18 , and their hypoactivity in R6/2 mice could disinhibit SST-INs leading to their hyperactivity, which would in turn lead to increased inhibition of CSPNs explaining their hypoactivity.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-0878f21c841f"
]
- source_span
VIP-INs are upstream of the other observed neuron types 9 – 11 , 18 , and their hypoactivity in R6/2 mice could disinhibit SST-INs leading to their hyperactivity, which would in turn lead to increased inhibition of CSPNs explaining their hypoactivity.
- evidence_refs
[
{
"ref": "paper:paper-0878f21c841f"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}