Details
- scope
- vip-interneurons
- section_id
- section_13
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-13-conclusion
- source_kind
- review_finding
- source_path
- evidence/section_13_evidence_package.json
- section_title
- Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- unevaluated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-13-conclusion
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
- claim_text
Here, we used longitudinal <i>in vivo</i> two-photon calcium imaging to examine the activity of two cortical inhibitory neuron (IN) subtypes and excitatory corticostriatal projection neurons (CSPNs) in the motor cortex of R6/2 HD mouse model throughout disease progression.
- raw_fields
{ "n": null, "doi": "10.1101/2025.02.07.637155", "pmid": "", "tags": [ "preprint_R4", "biorxiv_medrxiv" ], "year": "2025", "claim": "Here, we used longitudinal <i>in vivo</i> two-photon calcium imaging to examine the activity of two cortical inhibitory neuron (IN) subtypes and excitatory corticostriatal projection neurons (CSPNs) in the motor cortex of R6/2 HD mouse model throughout disease progression.", "pmcid": "", "round": 4, "title": "Optogenetic restoration of neuron subtype-specific cortical activity ameliorates motor deficits in Huntington’s Disease mice", "authors": "Sonja Blumenstock; David Arakelyan; Nicholas del Grosso; Sonja Schneider; Yufeng Shao; Enida Gjoni", "journal": "bioRxiv (Cold Spring Harbor Laboratory)", "citation": "Sonja Blumenstock et al. (2025). bioRxiv (Cold Spring Harbor Laboratory). 10.1101/2025.02.07.637155", "cite_key": "Blumenstock2025", "effect_size": null, "text_access": "fulltext", "citedByCount": 1, "isOpenAccess": "Y", "evidence_type": "in_vivo_function", "linked_topics": [ "locomotion", "arousal_state", "disease_models", "motor_learning", "prefrontal_VIP" ], "_source_cluster": "cluster_07_in_vivo_function", "relevance_score": 9.6, "replication_status": null, "_source_cluster_index": 142, "claim_source_sentence": "Here, we used longitudinal <i>in vivo</i> two-photon calcium imaging to examine the activity of two cortical inhibitory neuron (IN) subtypes and excitatory corticostriatal projection neurons (CSPNs) in the motor cortex of R6/2 HD mouse model throughout disease progression." }- source_refs
[ "paper:paper-0878f21c841f" ]
- source_span
Here, we used longitudinal <i>in vivo</i> two-photon calcium imaging to examine the activity of two cortical inhibitory neuron (IN) subtypes and excitatory corticostriatal projection neurons (CSPNs) in the motor cortex of R6/2 HD mouse model throughout disease progression.
- evidence_refs
[ { "ref": "paper:paper-0878f21c841f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }