Details

scope
mouse (auditory cortex injection; AAV tracing)
claim_text
GPe is positioned as a hub of an auditory cortico-basal-ganglia loop, with auditory cortex providing direct input to GPe and GPe projecting to auditory thalamic and cortical targets.
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json
effect_size
see source sentence
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-02
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
Notably, some GPe neurons project to the thalamus and cortex ( Mastro et al., 2014 ; Saunders et al., 2015 ; Abecassis et al., 2020 ), suggesting that the GPe may serve as an output nucleus within the cortico-basal ganglia loop.
study_system
mouse (auditory cortex injection; AAV tracing)
section_title
Classical Anatomy of the Triple Descending Projection
evidence_summary
Anatomical tracing of auditory cortico-GPe connections in mouse.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-02
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1523/eneuro.0161-24.2024",
  "claim": "GPe is positioned as a hub of an auditory cortico-basal-ganglia loop, with auditory cortex providing direct input to GPe and GPe projecting to auditory thalamic and cortical targets.",
  "cite_key": "Tomioka2024",
  "evidence": "Anatomical tracing of auditory cortico-GPe connections in mouse.",
  "effect_size": "see source sentence",
  "text_access": "fulltext",
  "study_system": "mouse (auditory cortex injection; AAV tracing)",
  "source_cluster_id": "cluster_02",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Notably, some GPe neurons project to the thalamus and cortex ( Mastro et al., 2014 ; Saunders et al., 2015 ; Abecassis et al., 2020 ), suggesting that the GPe may serve as an output nucleus within the cortico-basal ganglia loop.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "For the anterograde transneuronal tracing experiment, we injected 0.2 µl of adeno-associated virus [AAV; AAV1-CMV-HI-eGFP-Cre: 2.8 × 10 12 viral genomes per µl (vg/ml), Addgene Viral Prep#105545-AAV1; Addgene] into the primary auditory cortex (A1; bregma, −3.0 mm; lateral, 4.5 mm; depth, 0.5 mm) and 0.1 µl of AAV2-CAG-FLEX-tdTomato (1.2 × 10 13 vg/ml, University of North Carolina Vector Core) into the TS (bregma, −1.3 mm; lateral, 3.6 mm; depth, 2.7 mm)."
}
source_refs
[
  "paper:paper-5deb007e06d8"
]
evidence_refs
[
  {
    "ref": "paper:paper-5deb007e06d8"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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