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Systemically administered CNO does not enter the brain; instead, in vivo conversion of CNO to clozapine is responsible for DREADD activation, with subthreshold systemic clozapine d
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e0a9326449a8 — 5/17/2026, 4:35:28 PM (live)
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e0a9326449a8 — 5/17/2026, 4:35:28 PM (live)
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