MAPseq labels neurons with random barcoded RNA to map projections of thousands…

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scope: Mouse locus coeruleus barcoded RNA projection mapping
claim_text: MAPseq labels neurons with random barcoded RNA to map projections of thousands or millions of single neurons in parallel.
section_id: section_12
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
review_repo: ComputationalReviewLoops
section_ref: wiki_page:computationalreviewloops-12
source_kind: review_finding
source_path: evidence/section_12_evidence_package.json
source_span: Here we describe MAPseq (Multiplexed Analysis of Projections by Sequencing), a technique that can map the projections of thousands or even millions of single neurons by labeling large sets of neurons with random RNA sequences ("barcodes").
study_system: Mouse locus coeruleus barcoded RNA projection mapping
section_title: Whole-Brain Connectomics: Mouse, Primate, Human
evidence_summary: MAPseq is the foundational sequencing-based projectome method; recasting neuroanatomy as sequencing.
review_bundle_ref: analysis_bundle:ab-d49e54403ef9
replication_status: independently_replicated
review_package_ref: analysis_bundle:ab-d49e54403ef9
source_artifact_ref: wiki_page:computationalreviewloops-12
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
commit_sha: 0632aae8abc141909207fe91f6349b9e36489c3b
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewLoops

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1016/j.neuron.2016.07.036",
  "claim": "MAPseq labels neurons with random barcoded RNA to map projections of thousands or millions of single neurons in parallel.",
  "cite_key": "Kebschull2016",
  "evidence": "MAPseq is the foundational sequencing-based projectome method; recasting neuroanatomy as sequencing.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "Mouse locus coeruleus barcoded RNA projection mapping",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Here we describe MAPseq (Multiplexed Analysis of Projections by Sequencing), a technique that can map the projections of thousands or even millions of single neurons by labeling large sets of neurons with random RNA sequences (\"barcodes\").",
  "replication_evidence_dois": [
    "10.1038/nature26159",
    "10.1038/s41593-021-00842-4",
    "10.1038/s41467-024-52756-x"
  ],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-f6fa8c802d45"
]

evidence_refs

[
  {
    "ref": "paper:paper-f6fa8c802d45"
  }
]

source_policy

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MAPseq labels neurons with random barcoded RNA to map projections of thousands…

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Replication

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