Details

scope
mouse V1; opto + 2P
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-06-synaptic-properties
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
Top-down input modulates visual context processing through an interneuron-specific circuit
study_system
mouse V1; opto + 2P
section_title
Synaptic Properties and Connectivity
evidence_summary
Optogenetic stimulation of cingulate→V1 axons + 2P imaging of VIP/SST/PV/Pyr cells in mouse V1.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicates
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-06-synaptic-properties
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
Top-down inputs from cingulate cortex to V1 modulate visual context processing through INTERNEURON-SELECTIVE VIP→SST disinhibition; optogenetic activation of cingulate axons recruits VIP cells preferentially over PV/SST and enhances figure-ground segregation.
raw_fields
{
  "n": null,
  "doi": "10.1016/j.celrep.2023.113133",
  "claim": "Top-down inputs from cingulate cortex to V1 modulate visual context processing through INTERNEURON-SELECTIVE VIP→SST disinhibition; optogenetic activation of cingulate axons recruits VIP cells preferentially over PV/SST and enhances figure-ground segregation.",
  "title": null,
  "cite_key": "Bastos2023a",
  "evidence": "Optogenetic stimulation of cingulate→V1 axons + 2P imaging of VIP/SST/PV/Pyr cells in mouse V1.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse V1; opto + 2P",
  "_source_cluster": "cluster_05_synaptic_connectivity",
  "replication_status": "replicates",
  "_source_cluster_index": 79,
  "claim_source_sentence": "Top-down input modulates visual context processing through an interneuron-specific circuit",
  "replication_evidence_dois": [
    "10.1126/science.1254126",
    "10.1016/j.neuron.2020.11.013"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-45d83bfad56d"
]
evidence_refs
[
  {
    "ref": "paper:paper-45d83bfad56d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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