Details

scope
awake mouse ACa and V1 simultaneous recording + opto/chemogenetics
section_id
section_10
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
effect_size
ACa-V1 synchrony ~10 Hz; chemogenetic VIP silencing abolishes synchrony and deviance detection
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-10-oscillatory-dynamics
source_kind
review_finding
source_path
evidence/section_10_evidence_package.json
source_span
Local field potential recordings in mice during an oddball paradigm showed that ACa-V1 synchrony peaks in the theta/alpha band (≈10 Hz). Chemogenetic inhibition of V1-VIPs disrupted Aca-V1 synchrony and deviance detection in the V1.
study_system
awake mouse ACa and V1 simultaneous recording + opto/chemogenetics
section_title
Oscillatory Dynamics and Temporal Coordination
evidence_summary
Mouse anterior cingulate–V1 dual-LFP, two-photon imaging, optogenetics, and DREADD silencing of V1 VIP cells.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
single-study
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-10-oscillatory-dynamics
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_10_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
claim_text
In mouse V1 during an oddball paradigm, ACa–V1 synchrony peaks in the theta/alpha band (~10 Hz); 10-Hz optogenetic stimulation of ACa→V1 inputs activates V1 VIP and inhibits SST cells, and chemogenetic VIP silencing abolishes both ACa–V1 theta/alpha synchrony and V1 deviance detection.
raw_fields
{
  "n": null,
  "doi": "10.1016/j.celrep.2023.113133",
  "pmid": "37708021",
  "year": "2023",
  "claim": "In mouse V1 during an oddball paradigm, ACa–V1 synchrony peaks in the theta/alpha band (~10 Hz); 10-Hz optogenetic stimulation of ACa→V1 inputs activates V1 VIP and inhibits SST cells, and chemogenetic VIP silencing abolishes both ACa–V1 theta/alpha synchrony and V1 deviance detection.",
  "pmcid": "PMC10591868",
  "title": "Top-down input modulates visual context processing through an interneuron-specific circuit.",
  "authors": "",
  "journal": "",
  "cite_key": "Bastos2023a",
  "evidence": "Mouse anterior cingulate–V1 dual-LFP, two-photon imaging, optogenetics, and DREADD silencing of V1 VIP cells.",
  "cluster_id": "cluster_09_oscillations",
  "effect_size": "ACa-V1 synchrony ~10 Hz; chemogenetic VIP silencing abolishes synchrony and deviance detection",
  "figure_data": [],
  "text_access": "abstract_only",
  "study_system": "awake mouse ACa and V1 simultaneous recording + opto/chemogenetics",
  "cited_by_count": 51,
  "_source_cluster": "cluster_09_oscillations",
  "replication_status": "single-study",
  "_source_cluster_index": 23,
  "claim_source_sentence": "Local field potential recordings in mice during an oddball paradigm showed that ACa-V1 synchrony peaks in the theta/alpha band (≈10 Hz). Chemogenetic inhibition of V1-VIPs disrupted Aca-V1 synchrony and deviance detection in the V1.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "ACa-V1 synchrony peaks in the theta/alpha band (≈10 Hz)"
}
source_refs
[
  "paper:paper-45d83bfad56d"
]
evidence_refs
[
  {
    "ref": "paper:paper-45d83bfad56d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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