Details

scope
Mouse ACa → V1; LFP + 2P imaging + opto/chemogenetics
claim_text
Top-down ACa→V1 projections in mice synchronize with V1 in the theta/alpha band (~10 Hz) and drive deviance detection by activating V1 VIP and inhibiting SST interneurons.
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
ACa–V1 synchrony peaks at ~10 Hz; chemogenetic VIP silencing disrupts both ACa–V1 synchrony and deviance detection (qualitative).
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
Optogenetic drive of ACa-V1 inputs at 10 Hz activated V1-VIPs but inhibited V1-SSTs, mirroring the dynamics present during the oddball paradigm.
study_system
Mouse ACa → V1; LFP + 2P imaging + opto/chemogenetics
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
LFP recording during an oddball paradigm, two-photon imaging of V1 cell types, optogenetic drive of ACa→V1 inputs, and chemogenetic silencing of V1 VIP interneurons.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.celrep.2023.113133",
  "claim": "Top-down ACa→V1 projections in mice synchronize with V1 in the theta/alpha band (~10 Hz) and drive deviance detection by activating V1 VIP and inhibiting SST interneurons.",
  "cite_key": "Bastos2023",
  "evidence": "LFP recording during an oddball paradigm, two-photon imaging of V1 cell types, optogenetic drive of ACa→V1 inputs, and chemogenetic silencing of V1 VIP interneurons.",
  "effect_size": "ACa–V1 synchrony peaks at ~10 Hz; chemogenetic VIP silencing disrupts both ACa–V1 synchrony and deviance detection (qualitative).",
  "text_access": "abstract_only",
  "study_system": "Mouse ACa → V1; LFP + 2P imaging + opto/chemogenetics",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "Optogenetic drive of ACa-V1 inputs at 10 Hz activated V1-VIPs but inhibited V1-SSTs, mirroring the dynamics present during the oddball paradigm.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Local field potential recordings in mice during an oddball paradigm showed that ACa-V1 synchrony peaks in the theta/alpha band (≈10 Hz)."
}
source_refs
[
  "paper:paper-45d83bfad56d"
]
evidence_refs
[
  {
    "ref": "paper:paper-45d83bfad56d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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