- claim_text
Hodge et al. (2019) found that interneuron-discriminating gene sets were largely conserved between mouse and human, supporting alignment of homologous interneuron subtypes (~37 homologous t-types) despite species-specific expression differences.
- raw_fields
{
"n": null,
"doi": "10.1038/s41586-019-1506-7",
"claim": "Hodge et al. (2019) found that interneuron-discriminating gene sets were largely conserved between mouse and human, supporting alignment of homologous interneuron subtypes (~37 homologous t-types) despite species-specific expression differences.",
"title": null,
"cite_key": "Hodge2019",
"evidence": "MetaNeighbor cross-species mapping aligned ~37 homologous interneuron t-types between human MTG and mouse VISp/ALM; VIP and SST subclasses showed conserved markers but expanded type diversity in human.",
"effect_size": null,
"text_access": "fulltext",
"study_system": "human MTG vs mouse VISp/ALM; cross-species snRNA-seq",
"target_section": "section_02",
"_source_cluster": "cluster_01_molecular_taxonomy",
"replication_status": "replicated",
"_source_cluster_index": 6,
"claim_source_sentence": "Matching cell types requires shared expression patterns between species, and we find that gene families (mean = 21 genes/set) that best discriminate mouse interneurons also discriminate human interneurons."
}- source_refs
[
"paper:paper-pm-31435019"
]
- evidence_refs
[
{
"ref": "paper:paper-pm-31435019"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}