Details
- scope
- human neocortex; Patch-seq + enhancer-AAV labeling
- claim_text
- Jorstad et al. (2023) reported a human cortex GABAergic taxonomy of 45 transcriptomic types across four canonical interneuron subclasses (PVALB, SST, VIP, LAMP5/PAX6) using Patch-seq with enhancer-AAV labeling for VIP enrichment.
- section_id
- section_11
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_11_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-11-disease-translational
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- This taxonomy contains 45 GABAergic neuronal transcriptomic types across four canonical interneuron subclasses (PVALB, SST, VIP, and LAMP5/PAX6).
- study_system
- human neocortex; Patch-seq + enhancer-AAV labeling
- section_title
- Species Differences, Human Relevance, and Disease
- evidence_summary
- Human cortex Patch-seq with enhancer-AAV (CN2039) labeling enriched VIP recovery; VIP subclass shows diverse types with small soma + bipolar dendrites in L2/3; subclass-level morphoelectric separation confirmed.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-11-disease-translational
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_11_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1126/science.adf6484", "claim": "Jorstad et al. (2023) reported a human cortex GABAergic taxonomy of 45 transcriptomic types across four canonical interneuron subclasses (PVALB, SST, VIP, LAMP5/PAX6) using Patch-seq with enhancer-AAV labeling for VIP enrichment.", "title": null, "cite_key": "Lee2023a", "evidence": "Human cortex Patch-seq with enhancer-AAV (CN2039) labeling enriched VIP recovery; VIP subclass shows diverse types with small soma + bipolar dendrites in L2/3; subclass-level morphoelectric separation confirmed.", "effect_size": null, "text_access": "fulltext", "study_system": "human neocortex; Patch-seq + enhancer-AAV labeling", "target_section": "section_11", "_source_cluster": "cluster_01_molecular_taxonomy", "replication_status": "replicated", "_source_cluster_index": 17, "claim_source_sentence": "This taxonomy contains 45 GABAergic neuronal transcriptomic types across four canonical interneuron subclasses (PVALB, SST, VIP, and LAMP5/PAX6)." }- source_refs
[ "paper:paper-37824669", "paper:paper-430f33cd589f" ]
- evidence_refs
[ { "ref": "paper:paper-37824669" }, { "ref": "paper:paper-430f33cd589f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }