Paired recordings in mouse auditory cortex show that L2/3 → L5B corticocollicul…

Paired recordings in mouse auditory cortex show that L2/3 → L5B corticocollicular (PT-type) and L2/3 → L5B corticocallosal (IT-type) synaptic connections have similar unitary EPSC amplitude/kinetics but different short-term dynamics: corticocollicular connections show no depression while corticocallosal connections show substantial depression.

{
  "n": null,
  "doi": "10.1523/jneurosci.0836-14.2015",
  "claim": "Paired recordings in mouse auditory cortex show that L2/3 → L5B corticocollicular (PT-type) and L2/3 → L5B corticocallosal (IT-type) synaptic connections have similar unitary EPSC amplitude/kinetics but different short-term dynamics: corticocollicular connections show no depression while corticocallosal connections show substantial depression.",
  "cite_key": "Joshi2015",
  "evidence": "Acute-slice whole-cell paired recordings between L2/3 pyramidal neurons and retrogradely labelled corticocollicular vs corticocallosal L5B neurons in mouse auditory cortex.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse auditory cortex L5B corticocollicular (PT) and corticocallosal (IT) neurons",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "However, short trains of unitary EPSCs showed no synaptic depression in L2/3→corticocollicular connections, but substantial depression in L2/3→corticocallosal connections.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

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