Version history

1 version on record. Newest first; the live version sits at the top with a live indicator.

  1. Live sha256:7d63a
    4/30/2026, 2:41:24 PM
    Content snapshot 
    {
  "nct_id": "NCT03761849",
  "phase": "phase_3",
  "status": "terminated",
  "domain": "huntingtons",
  "indication": "Manifest Huntington's Disease",
  "intervention": "Tominersen (antisense oligonucleotide targeting HTT)",
  "sponsor": "Roche",
  "n_enrolled": 791,
  "primary_endpoint": "cUHDRS at 101 weeks",
  "summary": "Halted March 2021 — exploratory analyses suggested potential harm from non-allele-specific HTT lowering. Reframed the field around earlier intervention + allele-selective targeting.",
  "metadata": {}
}