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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Ceramide Signaling Pathway in Neurodegeneration
Ceramide["Ceramide"] Myriocin["Myriocin"] -.->|"downregulates"| Ceramide["Ceramide"] SPT["SPT"] -->|"catalyzes
Read more → - CERS6 Protein
Ceramide Synthase 6 CERS6 — Ceramide Synthase 6 Protein Name Ceramide
Read more → - ceramide-sphingolipid-modulation-therapy
Ceramide["Ceramide"] Myriocin["Myriocin"] -.->|"downregulates"| Ceramide["Ceramide"] SPT["SPT"] -->|"catalyzes
Read more → - CERS2 — Ceramide Synthase 2 (Lass2)
ceramide["ceramide"] CERS2["CERS2"] -->|"associated with"| ceramide["ceramide"] CERS2["CERS2
Read more → - CERS1 — Ceramide Synthase 1
ceramide 18:0 C20-ceramide 20:0 C16-ceramide 16:0 C14-ceramide
Read more →
Graph neighborhood (30 nodes · 55 edges)
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Related hypotheses
- Selective Acid Sphingomyelinase Modulation Therapy
sphingomyelinase (ASM, encoded by SMPD1) to restore ceramide homeostasis and ameliorate Alzheimer's disease pathology ... catalyzes the hydrolysis of sphingomyelin to ceramide in …
- Sphingomyelin Synthase Activators for Raft Remodeling
membranes — specifically the shift from sphingomyelin to ceramide — that disrupts synaptic signaling, promotes amyloidogenic processing ... drives neuronal apoptosis in neurodegen…
- Sphingolipid Metabolism Reprogramming
protein aggregation dynamics in neurodegenerative diseases. Ceramide synthases (CERS) constitute the rate-limiting enzymes ... novo ceramide biosynthesis, with six distinct isofor…
- Neutral Sphingomyelinase-2 Inhibition for Synaptic Protection in Neurodegeneration
SMPD3, catalyzes the hydrolysis of sphingomyelin to ceramide and phosphocholine at the plasma membrane, particularly ... MAPK and JNK pathways. The resulting ceramide accumulation…
- Senescent Cell ASM-Complement Cascade Intervention
acid sphingomyelinase (SMPD1) activity, leading to excessive ceramide production within membrane lipid rafts and endolysosomal ... compartments. This ceramide accumulation creates…