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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- HSPA1A Gene
HSPA1A -->|"inhibits"| APOPTOSIS HSPA1A -->|"inhibits"| PYROPTOSIS HSPA1A -->|"inhibits"| NEUROINFLAMMATION HSPA1A
Read more → - HSPA1A Protein
HSPA1A["HSPA1A"] PROT["Protein Folding"] HSPA1A -->|"mediates"| PROT style HSPA1A
Read more → - Heat Shock Protein 70 (HSPA1A)
HSPA1A -->|"associated with"| Functional_Recovery HSPA1A -->|"expressed in"| Oligodendrocytes HSPA1A
Read more → - HSP70 (Heat Shock Protein 70 / HSPA1A)
HSPA1A) HSP70 (Heat Shock Protein 70 / HSPA1A) Gene [HSPA1A](/entities/hspa1a
Read more → - Validated Hypothesis: Exposed amyloidogenic segments (β-sheet propensity residues) serve as HSP70 recognition codes
HSPA1A, DNAJB6, DNAJB2](https://www.ncbi.nlm.nih.gov/gene/?term=HSPA8, HSPA1A, DNAJB6, DNAJB2) - [UniProt
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Related hypotheses
- Isoform-Selective Hsp70 Targeting Overcomes Stoichiometric Imbalance in Advanced Pathology
Pathology starts from the claim that modulating HSPA1A, DNAJB6, DNAJB8 within the disease context ... Pathology starts from the claim that modulating HSPA1A, DNAJB6, DNAJB8 within…
- Hsp70-based therapy to prevent lysosomal membrane permeabilization and cathepsin release in AD
starts from the claim that modulating HSPA1A within the disease context of neuroscience can redirect ... starts from the claim that modulating HSPA1A within the disease context of…
- Transient Chaperone Priming Prior to Seed Inoculation Prevents Propagation by Reshaping Neuronal Proteostasis
claim that modulating HSF1, NFE2L2 (NRF2), HSPA1A, DNAJB1 within the disease context of protein folding ... claim that modulating HSF1, NFE2L2 (NRF2), HSPA1A, DNAJB1 within the di…
- Chaperone-Mediated APOE4 Refolding Enhancement
Enhancement starts from the claim that modulating HSPA1A, HSP90AA1, DNAJB1, FKBP5 within the disease context ... Heat shock protein 70 (HSP70), encoded by HSPA1A, serves as the pr…
- Proteostasis Enhancement via APOE Chaperone Targeting
Targeting starts from the claim that modulating HSPA1A within the disease context of neurodegeneration ... Framed more explicitly, the hypothesis centers HSPA1A within the broader…