No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- MLKL Gene
MLKL MLKL -->|"executes"| Necroptosis MLKL -->|"activates"| Autophagy MLKL -->|"regulates"| BECN1
Read more → - Necroptotic Neurons
MLKL (p-MLKL), active RIPK3, and elevated MLKL mRNA and protein
Read more → - Necroptosis Pathway in Neurodegeneration
MLKL (Mixed Lineage Kinase Domain-Like):** MLKL is the terminal
Read more → - Necroptosis in Neurodegeneration
MLKL Phosphorylation**: RIPK3 phosphorylates MLKL at Thr357 and Ser358 (human
Read more → - Necroptosis in Alzheimer's Disease
MLKL Recruitment"] I --> J["MLKL Phosphorylation"] J --> K["MLKL Oligomerization
Read more →
Graph neighborhood (30 nodes · 174 edges)
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Related hypotheses
- Paraneoplastic myelopathies involve CD8+ T cell recognition of viral/cancer antigens causing necroptotic neuronal death
CD8A, CD8B, PRF1, GZMB, RIPK3, MLKL within the disease context of neuroinflammation can redirect ... CD8A, CD8B, PRF1, GZMB, RIPK3, MLKL within the disease context of neuroinflamm…
- Necroptosis-cGAS Feedforward Loop Converts TDP-43 Pathology into Neuroinflammation
Neuroinflammation starts from the claim that modulating MLKL / RIPK1 within the disease context of neuroinflammation ... Neuroinflammation starts from the claim that modulating ML…