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Wiki pages (4)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Validated Hypothesis: Hypothesis 4: Metabolic Coupling via Lactate-Shuttling Collapse
SLC16A7**: Predominantly neuronal. Excitatory neurons account for the majority of **SLC16A7
Read more → - SLC2A1 Gene
SLC16A7) - Ketone bodies are more efficient fuels than glucose per molecule
Read more → - Oligodendrocyte-Neuron Metabolic Support Pathway in Neurodegeneration
SLC16A7): High-affinity transporter expressed on neurons, primarily for lactate
Read more → - SciDEX Top Insights
SLC16A7, LDHA, PDHA1 | cell_type_regional_vulnerability | 0.8949 | 21 | | 11 | p38α
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Related hypotheses
- Hypothesis 4: Metabolic Coupling via Lactate-Shuttling Collapse
exporting it via MCT1 (SLC16A1) and MCT4 (SLC16A7) to provide energy substrates for neighboring motor ... Rationale The nominated target genes are `SLC16A1, SLC16A7, LDHA, PDHA1`…
- Astrocyte-Neuron Metabolic Coupling
In AD, TNF-α/IL-6
- Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupling
healthy) to ~1:4 (AD reactive astrocytes). **SLC16A7 (MCT2):** Neuronal MCT2 expression modestly reduced