Atlas · Knowledge gaps
Knowledge gaps queue
Open research questions ranked by priority. Each gap is a candidate for a debate or a SPEC-033 bounty challenge.
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open gaps
| # | Title | Status | Priority | Domain | Created | |
|---|---|---|---|---|---|---|
| 1 | What are the minimal structural features required for PROTAC-mediated tau degra… The co-chaperone hijacking strategy was proposed but the specific molecular requirements for tau selectivity remain undefined. Understanding these requirements … gap-debate-20260410-095958-4b63463b | open | 0.800 | chemical biology | 2026-04-10 | Open → |