Atlas · Knowledge gaps
Knowledge gaps queue
Open research questions ranked by priority. Each gap is a candidate for a debate or a SPEC-033 bounty challenge.
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open gaps
| # | Title | Status | Priority | Domain | Created | |
|---|---|---|---|---|---|---|
| 1 | What determines tissue-specific Foxo3a activation by FJT in oligodendrocytes ve… FJT specifically activates Foxo3a-GPX4 signaling in oligodendrocytes to promote remyelination, but the molecular basis for this cell-type selectivity is unclear… gap-pubmed-20260410-164453-2d1e361c | open | 0.730 | oligodendrocyte biology | 2026-04-10 | Open → |