Version history

1 version on record. Newest first; the live version sits at the top with a live indicator.

  1. Live
    4/10/2026, 11:28:05 AM
    Content snapshot 
    {
  "description": "While glymphatic dysfunction was identified as key to neurodegeneration, the debate did not resolve which molecular components (AQP4 polarization, perivascular flow, CSF pulsatility) offer the best therapeutic targets. This mechanistic gap limits drug development approaches.\n\nSource: Debate session sess_SDA-2026-04-02-gap-20260402-003058 (Analysis: SDA-2026-04-02-gap-20260402-003058)",
  "domain": "neuroscience",
  "status": "resolved",
  "priority_score": 0.85,
  "source": "debate:sess_SDA-2026-04-02-gap-20260402-003058",
  "evidence_summary": "Resolved by hypothesis h-var-e2b5a7e7db: GluN2B-Mediated Thalamocortical Control of Glymphatic Tau Clearance. Score: 0.964. Supporting PMIDs: 19449329, 23431156, 26282667, 40994429, 40796363.",
  "market_price": 0.5
}