24 results for “Digital Biomarkers”. Showing 24 of 39,449.
Digital biomarkers in Parkinson's disease.
Digital biomarker (DB) assessments provide objective measures of daily life
From geroscience to precision geromedicine: Understanding and managing aging.
biomarkers of aging, clinical and digital biomarkers of aging, psychosocial
Precision therapeutic strategies for Alzheimer's disease: Amyloid β-targeted foundations and multimodal next-generation approaches.
biomarker, and digital profiling to optimise outcomes. Collectively, these advances
Design considerations for C9orf72 disease prevention trials.
biomarkers and digital health technologies, potential analytic frameworks and relevant
Harmonizing immunogenicity for AAV and LNP/mRNA modalities: best-practice panels for binding, neutralizing, and cellular assays with pre-existing immunity controls.
digital assays for critical biomarkers. FUTURE PERSPECTIVE: By implementing this
Biomarkers in Spinocerebellar Ataxias.
digital measures of gait variability and- in SCA2- sensory nerve amplitudes. Response biomarkers
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases.
biomarker panel. METHODS: Gene expression databases were searched (http://genomics.senescence.info/genes including GenAge, AnAge, LongevityMap, CellAge, DrugAge, Digital
Multi-omics integration in disease research.
biomarker discovery and therapeutic development. Integrating these datasets with neuroimaging and digital
Biological determinants of blood-based biomarker levels in Alzheimer's disease: role of nutrition, inflammation, and metabolic factors.
biomarkers-Aβ, p-tau, and neurofilament light chain (NFL). Individualized interpretation, stratified clinical trials, and digital
Better Sleep Now, Better Cognition Later? Predicting Cognitive Function Using A Machine Learning-Based Sleep EEG Brain Health Score.
digital and traditional NP performance more than a decade later. These findings support the potential of EEG-derived, data-driven scores as a biomarker
Neuropathology of Alzheimer's Disease.
digital spatial profiling have opened novel avenues for improvement of neuropathological diagnosis and advancing our understanding of underlying molecular processes. Finally, major strides in biomarker
The Glymphatic-Venous Axis in Brain Clearance Failure: Aquaporin-4 Dysfunction, Biomarker Imaging, and Precision Therapeutic Frontiers.
biomarkers can provide a measure of transport. Therapeutic strategies are rapidly advancing from experimental strategies to translational approval, including behavioral optimization, closed-loop sleep stimulation, vascular and lymphatic therapies, focused
Updates on Parkinson's Disease.
biomarker validation across ethnic cohorts (30% variability in α-synuclein thresholds) and non-motor symptom management. Emerging solutions leverage single-cell spatial transcriptomics identifying dopaminergic neuron vulnerability signatures, coupled with
Accelerating Biomedical Discoveries in Aging and Neurodegeneration Through Transformative Neuropathology
biomarkers, therapeutic targets, and complex disease patterns through comprehensive analyses of postmortem human brain tissue. Yet critical challenges, including sustainability of brain banks, expanding donor participation, strengthening training pipelines, enabling
Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration
biomarkers, therapeutic targets, and complex disease patterns through comprehensive analyses of postmortem human brain tissue. Yet critical challenges remain, including the sustainability of brain banks, expanding donor participation, strengthening training
Androgen receptor expression on circulating tumor cells in metastatic breast cancer.
biomarkers of interest (AR, estrogen receptor [ER], and HER2) on all nucleated cells. The stained slides were scanned and enumerated by non-enrichment-based non-biased approach independent of cell
Clinical trial design in the era of precision medicine.
digital apps and structured observational registries, and the utilization of machine learning and/or artificial intelligence, may further accelerate knowledge acquisition. Overall, clinical trials have evolved, shifting from tumor type-centered
Radiomics in colorectal cancer patients.
Digital Imaging and Communications in Medicine files: This image numerical analysis has been named "radiomics". Radiomics allows the extraction of quantitative features from radiological images, mainly invisible to the naked
Blood-Brain Barrier Overview: Structural and Functional Correlation.
Digital Library for the various cells and components that support the development and function of this barrier, as well as the different pathways to transport the various molecules between blood
Peripheral Markers of Neurovascular Unit Integrity and Amyloid-β in the Brains of Menopausal Women.
biomarkers for the diagnosis and prognosis of Alzheimer's disease and related dementias is more feasible at the population level than obtaining cerebrospinal fluid or neuroimaging markers. This study determined
Measurement of α-synuclein as protein cargo in plasma extracellular vesicles.
biomarkers. This promise has led to increased interest in measuring EV proteins from both total EVs as well as brain-derived EVs in plasma. However, measuring cargo proteins
Contact lens-based lysozyme detection in tear using a mobile sensor.
digital eye-strain by asking them to play a game on their mobile-phones during the CL wear-duration. We also observed a lower mean lysozyme concentration
Alzheimer's disease clinical variants show distinct neuroinflammatory profiles with neuropathology.
digital pathology. RESULTS: Phosphorylated tau was distinctly distributed in each variant. In all variants, amyloid-β was neocortical-dominant, with a notable increase in the middle frontal cortex of behavioural/dysexecutive
Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016.
biomarkers of hepatocellular carcinoma and cholangiocarcinoma via transcriptome microarray meta-analysis S. Likhitrattanapisal O24 Clinical validity and actionability of multigene tests for hereditary cancers in a large multi-center study