20 results for “Nature Genetics”.
Defining the consequences of genetic variation on a proteome-wide scale.
Nature. 2016 Jun 23;534(7608):500-5. doi: 10.1038/nature18270. Epub 2016 Jun 15. Defining the consequences of genetic
Massively Parallel Genetics
genetics has historically depended on the identification of individuals whose natural
Squid-derived chitin oligosaccharides are a chemotactic signal during colonization by Vibrio fischeri.
natural genetic competence, and serving as an attractant for chemotaxis
crisprQTL mapping as a genome-wide association framework for cellular genetic screens
naturally occurring, common genetic variants) and resolution (by linkage disequilibrium
Hepatic fat as clinical outcome and therapeutic target for nonalcoholic fatty liver disease.
natural history, genetics, imaging studies and therapeutic trials that support
The natural killer gene complex genetic locus Chok encodes Ly-49D, a target recognition receptor that activates natural killing.
Previously, we established that natural killer (NK) cells from C57BL/6
Decoding Alzheimer's disease through down syndrome: insights from a genetically defined population.
natural history of Alzheimer's disease, offering critical insights into genetic
Mouse lemur cell atlas informs primate genes, physiology and disease
genetic analysis by identifying naturally occurring nonsense mutations in three
Engineered systems of inducible anti-repressors for the next generation of biological programming.
genetic circuits have almost exclusively used naturally occurring transcriptional repressors
Genome-Wide Association Analysis across Endophenotypes in Alzheimer's Disease: Main Effects and Disease Stage-Specific Interactions.
genetic susceptibility for Alzheimer's disease (AD) is not yet fully understood. The heterogeneous nature
Alzheimer's disease: insights into pathology, molecular mechanisms, and therapy.
nature. In addition to genetic predispositions, the development of AD is influenced
The exploding genetic code.
genetic code, beyond what nature initially intended, has given chemical
Limbic-predominant age-related TDP43 encephalopathy (LATE) neuropathological change in neurodegenerative diseases.
genetic risk factors and nature of the cognitive impairments and dementia
Possibilities and efficiency of MSC co-transfection for gene therapy.
nature of MSCs. Therefore, genetic manipulation of MSCs can increase
Genetic and epigenetic targets of natural dietary compounds as anti-Alzheimer's agents.
genetic, epigenetic, and environmental factors. There are two main types of Alzheimer's disease, known as familial Alzheimer's disease (onset < 65 years) and late-onset or sporadic Alzheimer
An update on genetic frontotemporal dementia.
natural history studies of presymptomatic genetic FTD are now underway
A natural mutator allele shapes mutation spectrum variation in mice.
genetic modifiers of the mutation rate have not been identified in nature
Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains.
naturally aged rodents differently influenced genetic and biochemical features of senescent
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.
nature of these disorders. Recent genetic studies have identified variants
Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses.
genetic variants associated with age at natural menopause demonstrates a global