25 results for “Neurotransmitter Biology”. Showing 25 of 39,449.
Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson's disease models.
neurotransmitters, and antioxidants, unveiling their multifaceted biological functions. PEVs aided
Royal Jelly: Biological Action and Health Benefits.
neurotransmitters, flavonoids, and polyphenols, that underlie the remarkable biological and therapeutic
Gray matter structural and molecular signatures in Alzheimer's disease and late-life depression.
neurotransmitter signatures and cellular phenotypes, supporting the notion that the two disorders share common biological
Gray matter structural and molecular signatures in Alzheimer's disease and late-life depression.
neurotransmitter signatures and cellular phenotypes, supporting the notion that the two disorders share common biological
Prenatal alcohol exposure dysregulates the expression of clock genes and alters rhythmic behaviour in mice.
neurotransmitter systems (e.g. Oprm1, Slc17a8, Drd1, Gabra1). These findings underscore the impact of early alcohol exposure on biological
Parkinson's Disease and Dementia with Lewy Bodies: One and the Same.
biological definitions of Lewy body disease, which do not assign any particular importance to the dopamine system over other degenerating neurotransmitter
Synapsin 1 Ameliorates Cognitive Impairment and Neuroinflammation in Rats with Alzheimer's Disease: An Experimental and Bioinformatics Study.
neurotransmitters (acetylcholine (ACh), dopamine (DA), and 5-hydroxytryptophan (5-HT)) and markers of oxidative stress (glutathione (GSH), malondialdehyde (MDA), reactive oxygen species (ROS)). Molecular biology
Regulation of APP processing. Potential for the therapeutical reduction of brain amyloid burden.
neurotransmitters, growth factors, and cytokines--constitute a class of chemicals that might be useful to accelerate processing of APP into non-amyloidogenic, and biologically
The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term.
neurotransmitters; however, reports over the last few years indicate that the synaptic vesicle cluster probably plays a much broader and more fundamental role in synaptic biology
Frontotemporal Dementia, Where Do We Stand? A Narrative Review.
biological fluids. Of note, the promising information provided by neurophysiological investigations, i.e., electroencephalography and non-invasive brain stimulation techniques, concerning the alterations in brain networks and neurotransmitter
Modulation of Gut Microbiota Through Dietary Intervention in Neuroinflammation and Alzheimer's and Parkinson's Diseases.
biological processes. Some dietary patterns can affect neurodegenerative diseases' progression through gut microbiota composition, gut permeability, and the synthesis and secretion of microbial-derived neurotrophic factors and neurotransmitters
From high dilutions to digital biology: the physical nature of the biological signal.
biological function. A parallel can be drawn between this debate on the memory of water, which presumes that the action of molecules is mediated by an electromagnetic phenomenon
Heat exposure intervention, anxiety level, and multi-omic profiles: A randomized crossover study.
neurotransmitters. Metabolites such as BDNF, GABA, and glucocorticoids released by the adrenal glands are biomarkers of heat stress-induced anxiety. CONCLUSIONS: We have demonstrated a causal link between heat stress
Role of SNAREs in Neurodegenerative Diseases.
neurotransmitter release. Indeed, inhibition of the formation of the SNARE complex, defects in the SNARE-dependent exocytosis and altered regulation of SNARE-mediated vesicle fusion have been associated with neurodegeneration
Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain.
biologically meaningful signals missed by matched-TWAS. Shared signals across the four disorders were more prominent in the developing brain, involving genes such as H4C13, ZSCAN12P1, and FLOT1, and pathways
Metabolomic Markers in Attention-Deficit/Hyperactivity Disorder (ADHD) among Children and Adolescents-A Systematic Review.
biological mechanisms and diagnostic potentials. A thorough PubMed and Web of Knowledge search identified studies exploring blood/urine metabolites in ADHD-diagnosed or psychometrically assessed children and adolescents. Synthesis revealed intricate
High Glucose Restraint of Acetylcholine-Induced Keratinocyte Epithelial-Mesenchymal Transition Is Mitigated by p38 Inhibition.
biology and homeostasis outside the neural system. Keratinocytes (KCs) have a functional cholinergic mechanism, suggesting that they respond to Ach. However, the physiological role and mechanism by which Ach modulates
Integrating microbial genomics and neurotranscriptomics to understand the impact of probiotic strains on neurological health
biological replicates per condition) were analyzed using differential expression, WGCNA, and GSEA to capture transcriptomic responses. Multi-omics integration (CCA, DIABLO, SPIEC-EASI) linked microbial pathways with neuronal gene modules
Mitochondrial function-associated genes underlie cortical atrophy in prodromal synucleinopathies.
biological processes, cellular components, human disease gene terms, and cell types enriched in these gene expression patterns. We then used structural and functional neighbourhood analyses to assess whether the atrophy
Intracellular calcium homeostasis and its dysregulation underlying epileptic seizures.
Biological activities require a delicate balance between excitatory and inhibitory signals in the brain. Disruption of this balance could lead to neurological disorders, such as epilepsydue to a relative enhancement
Chaperone-mediated autophagy as a sex-specific modulator of synaptic proteostasis and neural function.
Biology provides compelling evidence that CMA actively remodels the synaptic proteome in a sex-specific manner. Using a conditional knockout strategy based on Lamp2a-floxed mice crossed with a Camk2a
Synuclein and Mitochondrial Dysfunction: Regulating the Protein Import Complex toward PD Treatment?
neurotransmitter release, becomes pathologically accumulated in PD, despite not being upregulated under physiological conditions. Intracellular aggregation of αSyn into Lewy bodies is a hallmark of synucleinopathies. A vital facet
Ophiopogon polysaccharide can improve memory impairment induced by sleep deprivation in aged rats by regulating gut microbiota and inhibiting TLR4/NF-κB pathway in hippocampus.
biological analyses.The anti-inflammatory and neuroprotective effects of OPS were further validated in LPS-stimulated BV2 microglial cells and a BV2-HT22 co-culture system. The results demonstrated that
Neurobiological and therapeutic landmarks of depression associated with Alzheimer's disease dementia.
neurotransmitter dysregulation, neuroinflammation, abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis, and deficits in neuroplasticity. These mechanisms likely contribute to the acceleration of neurodegeneration in AD and the onset
The dementias.
neurotransmitter function, intervention at the level of amyloid production and deposition, and reduction of secondary risk factors such as hypertension, depression, and hypolipidaemia. Molecular diagnostic testing and genetic counselling