25 results for “Protein Design”. Showing 25 of 39,449.
De novo design of protein structure and function with RFdiffusion
protein monomer design, protein binder design, symmetric oligomer design, enzyme
Robust deep learning-based protein sequence design using ProteinMPNN.
protein designs have been generated using physically based approaches such
De novo design of protein structure and function with RFdiffusion
functional site scaffolding, symmetric oligomer design, and protein binder design.
Designed endocytosis-inducing proteins degrade targets and amplify signals.
Designed endocytosis-inducing proteins degrade targets and amplify signals. Huang
Multiplex design and discovery of proximity handles for programmable proteome editing
protein design to a multiplex screening framework could address this
Removing T-cell epitopes with computational protein design
protein design method for reducing immunogenicity by eliminating known and predicted
Design of protein-binding proteins from the target structure alone
design of binding proteins to 12 diverse protein targets with
Sounds interesting: can sonification help us design new proteins?
with high level parameters to achieve certain protein design features.
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2
design of self-assembling protein nanoparticle immunogens that elicit potent
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2
design of self-assembling protein nanoparticle immunogens that elicit potent
De novo design of potent and selective mimics of IL-2 and IL-15
designing proteins that recapitulate the binding sites of natural cytokines
Homology Modeling and Protein Interaction Map of CHRNA7 Neurogenesis Protein.
designing. Protein interaction analysis shows that CHRNA7 protein also interact
A synthetic protein-level neural network in mammalian cells.
designed protein heterodimers and engineered viral proteases to implement a synthetic
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.
Protein Design, University of Washington, Seattle, WA 98109, USA. (5)Department
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.
design protein engineering, we have developed a fully humanized and manufacturable
Targeted protein degradation for cancer therapy.
proteins. Since its conception over 20 years ago, TPD has gained a lot of attention mainly due to improvements in the design
A proimmunotoxin nanodrug targeting AIDS-associated non-Hodgkin lymphoma.
protein, ch128.1Av, designed to deliver biotinylated therapeutic agents into cancer
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
proteins by designing a series of proteolysis targeting chimeras (PROTACs
Molecular aspects of dopaminergic neurodegeneration: gene-environment interaction in parkin dysfunction.
protein inclusions, designated Lewy bodies and Lewy neurites. PD is one of the most
A de novo peptide hexamer with a mutable channel.
design of new proteins that expand the repertoire of natural
Unstructured polypeptides as a versatile drug delivery technology.
designed polypeptides to manipulate the performance of proteins and peptides
Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions.
design of mediators of protein-protein interactions (PPIs). Computational methods
A Polyaminobiaryl-Based β-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APP
proteins. A pharmacophoric design, novel drug synthesis, and structure-activity
Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex
protein cascades with designer receptors, we found that the activation
Multifunctional and biodegradable self-propelled protein motors.
protein motors enable design, control, and actuation strategies in microrobotics