25 results for “Protein Engineering”. Showing 25 of 39,449.
Stepwise Preparation of a Polymer Comprising Protein Building Blocks on a Solid Support for Immunosensing Platform.
protein (BCCP). Here, we employed two types of engineered proteins
Engineering chimeric signaling proteins for microbial whole-cell biosensors: from design to deployment.
protein engineering are expanding the versatility and specificity of these
Engineering therapeutic protein disaggregases.
protein disaggregase from yeast, have been engineered to robustly disaggregate
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
protein replacement strategy by engineering protein transport vehicle (PTV):PGRN
Heterotrimeric G protein signaling without GPCRs: The Gα-binding-and-activating (GBA) motif.
protein coupling for experimental therapeutics purposes, including the development of rationally engineered
Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging
protein engineering have significantly increased the performance of GECIs. The state
Recent progress in protein-protein interaction study for EGFR-targeted therapeutics.
protein engineering, novel bio-therapeutic approaches were developed and tested
Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation.
protein engineering techniques to create a highly effective cytosine base
A synthetic protein-level neural network in mammalian cells.
protein heterodimers and engineered viral proteases to implement a synthetic
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors.
protein engineering, we have developed a fully humanized and manufacturable
TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome.
protein engineering and empirical testing, the TRUPATH suite of Gαβγ
Integrating biocatalysis with continuous flow: current status, challenges, and future perspectives.
protein engineering and materials design, as well as computer-aided
Massively parallel single-amino-acid mutagenesis
protein engineering, and the interpretation of variants identified by clinical
Identification and enhanced activity of the tyrosine phenol-lyase from Mycobacterium tuberculosis.
protein engineering of Mt-TPL was undertaken using a consensus
The exploding genetic code.
protein engineering and biological studies. This special issue highlights some
Bacterial polyynes uncovered: a journey through their bioactive properties, biosynthetic mechanisms, and sustainable production strategies.
protein engineering to establish more robust and stable platforms for their
IgG Fusion Proteins for Brain Delivery of Biologics via Blood-Brain Barrier Receptor-Mediated Transport.
proteins has been engineered using genetically engineered MAbs directed to either
A Constrained Degron Tag Engineered to Enhance Auxin-Inducible Protein Degradation.
protein (GFP). The resulting engineered GFP variant, termed the "constrained
Nanobiotechnology-based drug delivery in brain targeting.
protein (LPR) with engineered peptide compound (EpiC) formed the platform
Transferrin receptor targeting chimeras for membrane protein degradation.
protein degradation. TransTACs are engineered to drive rapid co-internalization
Multifunctional Engineered Metal-Organic Frameworks as Targeted Protein Degraders for Augmenting Cancer Therapy via Hexokinase 2 Degradation and Provoking Cuproptosis.
engineered nanoparticle-based targeted protein degraders facilitated a new paradigm
A de novo peptide hexamer with a mutable channel.
provide a basis for engineering de novo proteins with new functions.
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
engineered Wnt3aWG EVs are generated by co-expressing Wnt3a with two genes encoding the membrane protein
Cre-dependent DREADD (Designer Receptors Exclusively Activated by Designer Drugs) mice.
engineered G protein-coupled receptors (GPCR) which can precisely control
H-bonded organic frameworks as ultrasound-programmable delivery platform.
engineered G-protein-coupled receptors in the ventral tegmental area