25 results for “Stroke Medicine”. Showing 25 of 39,449.
Gasdermin D could be lost in the brain parenchyma infarct core and a pyroptosis-autophagy inhibition effect of Jie-Du-Huo-Xue decoction after stroke.
The Chinese ethnic medicine Jie-Du-Huo-Xue Decoction (JDHXD
Buyang Huanwu decoction promotes post-stroke white matter repair via TREM2-Dependent microglial phagocytosis and IGF1 secretion.
stroke represents a critical pathological determinant of persistent neurological impairment, with current therapeutic options remaining limited. Buyang Huanwu Decoction (BYHWD), a time-honored formulation historically deployed in traditional Chinese medicine
Traditional Chinese herbal medicines for the treatment of ischemic stroke in China.
stroke (IS) is a devastating disease with high disability and mortality rates worldwide. Despite advances in medical treatment, managing IS remains a significant challenge. In China, traditional Chinese herbal medicines
Enhancing quality of life for survivors of stroke through phenomenology.
medicine. Twenty-two years later, survivors of stroke and their
Understanding the Pathophysiology of Ischemic Stroke: The Basis of Current Therapies and Opportunity for New Ones.
stroke, including molecular and cellular changes. This is followed by a highlight of drugs, cellular therapies, and complementary medicines
Multi-omics and experimental validation reveal the mechanism of DanxiaTiaoban decoction in treating atherosclerosis.
stroke, significantly impacting patients' health. Danxia Tiaoban Decoction (DXTB), a traditional Chinese medicine
Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia.
medicines to treat diseases caused by "kidney deficiency" such as cerebral arteriosclerosis, aging-related stroke
Diankuang Mengxing Decoction exerts neuroprotective effects in post-stroke depression by mediating the activation of the Wnt/β-catenin pathway via TREM2.
stroke and is typified by a depressed mood and loss of interest. A traditional Chinese medicine
Traditional Chinese Medicine for Cerebral Ischemia-Reperfusion Injury Prevention: Molecular Mechanisms and Future Perspectives.
stroke. The intricate pathological mechanisms involved include oxidative stress, neuroinflammation, and various forms of cell death, characterized by interactions between multiple signaling pathways. Natural products, such as traditional Chinese medicines
Reducing neuroinflammation through PKCγ/p38/NF-κB signaling pathway: the mechanism of Danzhi Xiaoyaosan in improving post-stroke depression.
stroke, causing tremendous mental burden to patients. Danzhi Xiaoyao San (DZX) is a widely used traditional Chinese medicine
The Protective Effect of DiDang Tang Against AlCl3-Induced Oxidative Stress and Apoptosis in PC12 Cells Through the Activation of SIRT1-Mediated Akt/Nrf2/HO-1 Pathway.
medicine for promoting blood circulation and removing blood stasis and collaterals, is widely used for the treatment of stroke
The Prevalence and Determinants of Using Traditional Chinese Medicine Among Middle-aged and Older Chinese Adults: Results From the China Health and Retirement Longitudinal Study.
medicine (TCM) is known as an integrative part of China's health care system, little is known on the prevalence and determinants of using TCM among the middle-aged
Elucidation of the mechanism of Yiqi Tongluo Granule against cerebral ischemia/reperfusion injury based on a combined strategy of network pharmacology, multi-omics and molecular biology.
stroke is caused by local lesions of the central nervous system and is a severe cerebrovascular disease. A traditional Chinese medicine
Naoxintong capsule attenuates heart damage after ischemic stroke via Nuclear factor-κB / Pyrin domain-containing protein 3 / Caspase-1 signaling.
stroke (IS) is a major cause of mortality. Inflammation exerts an essential part of brain-heart communication after IS. Naoxintong capsule (NXT), derived from the classical Traditional Chinese Medicine
Shexiang Tongxin dropping pills protect against ischemic stroke-induced cerebral microvascular dysfunction via suppressing TXNIP/NLRP3 signaling pathway.
stroke (IS) often continue to exhibit cerebral microcirculatory dysfunction even after receiving thrombolytic therapy. Enhancing the function of cerebral microvascular endothelia represents a pivotal advancement in the therapeutic strategy
Blood-Brain Barrier (BBB) Dysfunction in CNS Diseases: Paying Attention to Pericytes.
stroke, with a particular focus on the role of pericytes in BBB dysfunction. In addition, we also discuss treatments based on pericytes, such as regenerative medicine
Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH.
Stroke. 2023 Sep;54(9):2420-2433. doi: 10.1161/STROKEAHA.123.043005. Epub 2023 Jul 19. Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH. Chen
Profiling Tight Junction Protein Expression in Brain Vascular Malformations.
Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain. (3)Department of Neurosurgery, Institute of Neuroscience, Hospital Clinic of Barcelona, 08036 Barcelona, Spain. (4)Comprehensive Stroke
Border-associated macrophages in the central nervous system.
stroke, and gliomas. The elucidation of the heterogeneity and diverse functions of BAMs during homeostasis and neuroinflammation is mesmerizing, since it may shed light on the precision medicine
Border-associated macrophages in the central nervous system.
stroke, and gliomas. The elucidation of the heterogeneity and diverse functions of BAMs during homeostasis and neuroinflammation is mesmerizing, since it may shed light on the precision medicine
Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5).
Medicine, South China University of Technology, Guangzhou, China. Blood-brain barrier (BBB) disruption is a key event in triggering secondary damage to the central nervous system (CNS) under stroke
Theacrine protects vascular endothelial cells against oxidative damage after ischemic stroke by inhibiting Rac1 and activating Nrf2 pathway.
stroke is a leading global health issue without a definitive treatment. Theacrine (TC), a purine alkaloid extracted from Chinese tea kucha (Camellia assamica var. kucha), has shown potential in brain
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Medicine of the Austrian Academy of Sciences, Vienna, Austria. christoph.binder@meduniwien.ac.at. (#)Contributed equally Comment in Nat Rev Drug Discov. 2021 Oct;20(10):740. doi: 10.1038/d41573-021-00152-1. Atherosclerotic cardiovascular disease causes
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.
Stroke, NIH, Bethesda, MD, USA. (4)Queen Square Brain Bank, UCL Queen Square Institute of Neurology, University College London, London, UK. (5)Department of Neurodegenerative Disease, UCL Queen Square Institute
Microglia Mitochondrial Metabolism in Neurological Diseases.
stroke outcomes following microglial depletion. By synthesizing these mechanistic insights with lessons from failed clinical trials, we identify critical translational gaps-including the lack of longitudinal human data and validated