25 results for “Synaptic Neurobiology”. Showing 25 of 39,449.
Molecular pathways of major depressive disorder converge on the synapse.
neurobiology. In particular, considering the pattern of synaptic activity as the closest
A de novo convergence of autism genetics and molecular neuroscience
synaptic function. These pathways and genes significantly expand the neurobiological
Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration.
neurobiology of SGP-2 encompasses the subjects of cell death, synaptic
Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model.
synaptic loss in the medial prefrontal cortex (mPFC) and hippocampus. The current review presents a novel integrative model of neuroplasticity as a multi-domain neurobiological
Auditory processing deficits in autism spectrum disorder: mechanisms, animal models, and therapeutic directions.
neurobiological mechanisms underlying these deficits, including structural and functional disruptions in the auditory cortex, imbalances in excitatory and inhibitory signaling, and synaptic
Glycogen synthase kinase-3 signaling in Alzheimer's disease.
synaptic function. The present review summarizes the current understanding of the GSK3-β neurobiology
Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders.
neurobiological deficits. Brain derived neurotrophic factor (BDNF) is an extensively studied neurotrophin. BDNF is essential for neuronal genesis, differentiation, survival, growth, plasticity, synaptic
Neurobiology of alpha-synuclein.
Alpha-synuclein is an abundant neuronal protein that has been
Bidirectional regulation by "star forces": Ionotropic astrocyte's optical stimulation suppresses synaptic plasticity, metabotropic one strikes back.
synaptic plasticity, metabotropic one strikes back. Maltsev A(1), Roshchin M(1), Bezprozvanny I(2)(3), Smirnov I(1), Vlasova O(2), Balaban P(1), Borodinova A(1). Author information
The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease.
neurobiological and systems neurophysiological levels. By engaging distinct pre- and postsynaptic structures within the stimulated neural network, it directly or indirectly influences various cellular and molecular components. In AD, rTMS
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
synaptic impairments in neurons. Zhang X(1), Wei M(1), Fan J(1), Yan W(1), Zha X(1), Song H(1), Wan R(1), Yin Y(1), Wang
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.
synaptic structure and function genes (for example, PCLO, NCAM1 and PDE4B) and endocrine or immune regulators (for example, ESR1, TRAF3 and TANK). Additional top genes influence stress, immune, fear
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition.
neurobiology of VPS35 and Parkinson's disease mutation effects in the D620N knock-in mouse and the effect of leucine-rich repeat kinase 2 (LRRK2) inhibition on synaptic
The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease.
Alzheimer's disease (AD) is the most common form of
The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease.
Alzheimer's disease (AD) is the most common form of
Linearizing Voltage-Dependent Currents
synaptic input in the presence of voltage-dependent channels will lead to a local depolarization, followed by a hyperpolarization. Those of us who built our own radios will recognize such
Complement C1q/C3-CR3 signaling pathway mediates abnormal microglial phagocytosis of synapses in a mouse model of depression.
Neurobiology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China; Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan University, Shanghai 200433, China. Electronic address
The Potential Functions and Beneficial Effects of Melatonin on Cognitive Impairment, Neuroinflammation, Blood-Brain Barrier Leakage, and Synaptic Dysfunction in the Offspring of Mice Exposed to Gestational Intermittent Hypoxia.
neurobiological changes in GIH-exposed offspring and the mechanism underlying maternal melatonin supplementation in preventing these alterations using a murine model. METHODS: C57BL/6J mice were exposed to GIH between gestational
Running from Stress: Neurobiological Mechanisms of Exercise-Induced Stress Resilience.
synaptic plasticity as well as a reduction in the inflammatory factors. Studies published so far show that the energy challenge caused by physical exercise can affect the CNS by improving
Glucagon-like peptide-1 receptor agonists for major neurocognitive disorders.
neurobiological processes. In vitro and animal studies have revealed promising signals of neuroprotection, with preliminary supportive evidence emerging from recent pharmacoepidemiological investigations and clinical trials. In this article, we comprehensively
Memory impairment mediated by deoxynivalenol via the BLA-PrL circuit.
synaptic transmission in the PrL and reduces dendritic complexity and spine density. Notably, activation of BLA-PrL glutamatergic projections alleviated memory impairment induced by DON. Furthermore, our research utilized spatial
Regulator of G protein signaling 6 (RGS6) in ventral tegmental area (VTA) dopamine neurons promotes EtOH seeking, behavioral reward and susceptibility to relapse.
neurobiological mechanisms underlying EtOH-seeking behavior and dependence are not fully understood, and abstinence remains the only effective way to prevent alcohol use disorders (AUDs). Here, we developed novel RGS6
Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA. (7)Prothena Biosciences, Dublin, Ireland. (8)Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts
Complement, Inflammasome, and Microglial Crosstalk in Glaucoma: From Neurodegeneration to Immune-Based Precision Therapy.
Neurobiology, Institutes of Brain Science and Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China. Glaucoma is no longer viewed solely as a pressure-mediated optic neuropathy
Neurofilament Light Chain (NfL) in Blood-A Biomarker Predicting Unfavourable Outcome in the Acute Phase and Improvement in the Late Phase after Stroke.
neurobiological processes. In the acute and post-acute phase after stroke, high blood levels of NfL are associated with poor clinical outcome, and later on, the blood levels