10 results for “ad-risk”. Showing 10 of 39,449.
Human microglial state dynamics in Alzheimer's disease progression.
AD-risk genes in microglial states and differential expression of
CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk.
risk for Alzheimer's disease (AD). The full-length CD33 M isoform, whose expression is upregulated by non-coding
CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.
AD-risk allele. Analysis of CD33 isoforms identified a common
Associations between air pollution and markers of neuroinflammation, synaptic dysfunction and core Alzheimer's disease pathology vary by APOE genotype.
AD-risk enriched cohort, AP was not associated with MCI/AD
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
AD-risk genes were highly represented within homeostatic microglia suggesting
Multi-omics analysis for identifying cell-type-specific and bulk-level druggable targets in Alzheimer's disease.
AD-risk variant associated with candidate causal gene PABPC1 is located
Structural variation detection and association analysis of whole-genome-sequence data from 16,543 Alzheimer's disease sequencing project subjects.
AD-risk variants, exemplified by a 5k deletion in LD (R2 = 0.99) with
CLU alleviates Alzheimer's disease-relevant processes by modulating astrocyte reactivity and microglia-dependent synaptic density.
AD-risk alleles are associated with reduced CLU protein and heightened
10.1038/s41598-022-21496-7
AD-risk genes in GABAergic neuron subclasses, facilitating the GABAergic
Microglia in Alzheimer's Disease in the Context of Tau Pathology.
AD-risk genes (APOE, TREM2, and CD33) in tau pathology