25 results for “hsv-1”. Showing 25 of 39,449.
Molecular Mechanisms for Herpes Simplex Virus Type 1 Pathogenesis in Alzheimer's Disease.
HSV-1) as a causative agent in the pathogenesis of sporadic
JAG1 mediates apoptosis in herpes simplex keratitis by suppressing autophagy via ROS/JAG1/NOTCH1/pULK1 signaling pathway.
HSV-1-infected human CECs and in HSK mice. HSV
MLKL‒OPTN axis regulates herpesvirus-induced neurological sequelae.
-1 (HSV-1) infections are lifelong and linked to neurological
HSV-1 reactivation results in post-herpetic neuralgia by upregulating Prmt6 and inhibiting cGAS-STING.
HSV-1 load. Our findings revealed that HSV-1 escapes
HSV-1 and Cellular miRNAs in CSF-Derived Exosomes as Diagnostically Relevant Biomarkers for Neuroinflammation.
HSV-1 latency-associated ICP0 inversely correlated with lower HSV
Herpes simplex virus-1 infection alters microtubule-associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease.
HSV-1) infection alters critical markers of Alzheimer's disease
Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity.
-1 [HSV-1], human cytomegalovirus [HCMV], Equine herpesvirus-1 [EHV-1
Alzheimer's disease plaques and tangles: cemeteries of a pyrrhic victory of the immune defence network against herpes simplex infection at the expense of complement and inflammation-mediated neuronal destruction.
HSV-1) binding proteins (by 11 and 15 fold respectively
Rhoifolin prevents herpes simplex virus encephalitis by modulating SESN2 to regulate the Keap1/Nrf2 and AMPK/Nox pathways to inhibit neuro-oxidative damage in mice.
HSV-1 infection. HSV-1 infection can affect various brain
Metformin attenuates HSV-1-induced neuropathic pain by restoring Sirt3-mediated mitophagy.
HSV-1) infection induces a similar neuropathological process, a corresponding
Microglia innate immune response contributes to the antiviral defense and blood-CSF barrier function in human choroid plexus organoids during HSV-1 infection.
HSV-1) infection and found ChP epithelial cells were highly
Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology.
HSV-1), not p-tau, propagates this interneuronal, transsynaptic pathologic
Effects of Ilex paraguariensis A. St. Hil. (yerba mate) on herpes simplex virus types 1 and 2 replication.
HSV-1 and HSV-2 by a viral plaque number
Microglial cells initiate vigorous yet non-protective immune responses during HSV-1 brain infection.
HSV)-1 triggers neuroinflammatory responses leading to peripheral immune cell
Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.
HSV-1 but not the RNA virus VSV. Chemical blockade
Anti-herpetic tau preserves neurons via the cGAS-STING-TBK1 pathway in Alzheimer's disease.
HSV-1) being a leading candidate. Our investigation, using metagenomics
Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production.
HSV-1-infected brain through a mechanism dependent on the cyclic
TRIM23 mediates cGAS-induced autophagy in anti-HSV defense.
HSV-1 infection. HSV-1 infection or cGAS-STING stimulation
Determination of the effects of
HSV-1 structural proteins, glycoprotein B (HSV-gB) may influence
Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.
HSV-1) infection in primary human fibroblasts. We compare several
Microbial infection instigates tau-related pathology in Alzheimer's disease via activating neuroimmune cGAS-STING pathway.
HSV-1 strain (mHSV-1) potentially relevant to AD, we found
Interactions between the products of the Herpes simplex genome and Alzheimer's disease susceptibility genes: relevance to pathological-signalling cascades.
HSV-1) genome interact with many Alzheimer's disease susceptibility
Microbial infection promotes amyloid pathology in a mouse model of Alzheimer's disease via modulating γ-secretase.
-1) and found that its hippocampal infection locally promotes Aβ pathology in 5 × FAD mice, the commonly used amyloid model. Mechanistically, we identified HSV
Inverse relationship between Alzheimer's disease and cancer, and other factors contributing to Alzheimer's disease: a systematic review.
-1, HSV, TDP-43, APOE variants, notch signals and presenilins
A robust ex vivo experimental platform for molecular-genetic dissection of adult human neocortical cell types and circuits.
HSV-1 vectors, with virally-transduced neurons exhibiting membrane properties