25 results for “protein aggregation”. Showing 25 of 39,449.
Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles.
protein aggregation. Proteomic analysis of Gba1b mutants revealed dysregulation of proteins
Regulated protein aggregation: stress granules and neurodegeneration
protein aggregation that occurs in neurodegenerative diseases is classically thought
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
protein aggregates with little liquidity (solid aggregates). Furthermore, aggregation-prone
Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance.
protein aggregate formation resembling coiled bodies, which are characteristic for PSP and CBD. Large
Pro-cathepsin D prevents aberrant protein aggregation dependent on endoplasmic reticulum protein CLN6.
protein aggregation, we isolated proteins that bind to the ER-anchored
HYPK coordinates degradation of polyneddylated proteins by autophagy.
protein aggregates, such as aggregates of mutant HTT exon 1. Thus
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity.
protein aggregates and ectopically expressed aggregation-prone proteins. CCDC50 recognizes
Protein quality control systems in neurodegeneration - culprits, mitigators, and solutions?
protein aggregation in NDDs, describing the interactions of aggregated proteins
The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation.
protein aggregation, including Huntington's disease and amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis and Autophagy: Dysfunction and Therapeutic Targeting.
proteins, inclusions, and aggregates within motor neurons is the main
Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias.
protein aggregates. In neural cells, toxic polySer and polyLeu proteins
Protein aggregation and neurodegenerative disease.
protein aggregation and inclusion body formation. The aggregates usually consist
Interaction between autophagy and the NLRP3 inflammasome in Alzheimer's and Parkinson's disease.
protein aggregates is one of the standard features of Neurodegenerative
Stress granule mediated protein aggregation and underlying gene defects in the FTD-ALS spectrum.
protein aggregation in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis
Seeing the Unseen: Super-Resolution Microscopy in Protein Aggregation Research.
protein aggregation, with a focus on aggregate morphology, dynamic formation
The role of microglia in the prion-like transmission of protein aggregates in neurodegeneration.
protein aggregation in the CNS. Microglia, the brain's innate
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.
protein aggregation is associated with neurodegeneration and other pathologies. The nature
RNA G-quadruplexes mediated protein aggregation in neurodegenerative diseases.
protein co-aggregation and pathological protein aggregation in NDs. Here
Inertial Agitation in an NMR Magnet: Real-Time Monitoring of Protein Aggregation at High Resolution.
protein aggregation directly inside an NMR magnet. In this approach
Molecular Mechanisms of Protein Aggregation in ALS-FTD: Focus on TDP-43 and Cellular Protective Responses.
aggregation of proteins, including Cu/Zn superoxide dismutase (SOD1), transactive response
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds.
protein aggregates into the extracellular space. Free aggregates then enter
Viral vector gene delivery of the novel chaperone protein SRCP1 to modify insoluble protein in in vitro and in vivo models of ALS.
Protein misfolding and aggregation are shared features of neurodegenerative diseases
The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol.
protein aggregates via the unfolded protein response, the proteasome-ubiquitin
Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases.
protein aggregates formed by mutant huntingtin protein containing expanded polyglutamine
Inhibition of amyloid beta oligomer accumulation by NU-9: A unifying mechanism for the treatment of neurodegenerative diseases.
Protein aggregation is a hallmark of neurodegenerative diseases, which connects