25 results for “pyroptosis”. Showing 25 of 39,449.
Mechanism of Resveratrol on LPS/ATP-induced pyroptosis and inflammatory response in HT29 cells.
pyroptosis. RES down-regulates the pyroptosis of HT29 cells induced
Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination.
pyroptosis. Pyroptosis inhibitor was further used to investigate the role
Microglial pyroptosis in hippocampus mediates sevolfurane-induced cognitive impairment in aged mice via ROS-NLRP3 inflammasome pathway.
pyroptosis in the cognitive impairment model. NSA effectively inhibited the pyroptosis
Gasdermin D could be lost in the brain parenchyma infarct core and a pyroptosis-autophagy inhibition effect of Jie-Du-Huo-Xue decoction after stroke.
pyroptosis and autophagy after MCAO/R. JDHXD suppressed pyroptosis and autophagy
Aloe-emodin alleviates cerebral ischemia-reperfusion injury by regulating microglial polarization and pyroptosis through inhibition of NLRP3 inflammasome activation.
pyroptosis exacerbates ischemic injury. NOD-like receptor protein 3 (NLRP3
TLR2 signalling triggers NLRP3 inflammasome-mediated microglial pyroptosis promotes neonatal hypoxic-ischemic brain injury.
pyroptosis-related proteins, reversing pyroptosis features. Additionally, TLR2 inhibition decreased
HSPA1A inhibits pyroptosis and neuroinflammation after spinal cord injury via DUSP1 inhibition of the MAPK signaling pathway.
pyroptosis and inflammation. CONCLUSION: HSPA1A reduces pyroptosis and inflammation after
Luteolin rescues postmenopausal osteoporosis elicited by OVX through alleviating osteoblast pyroptosis via activating PI3K-AKT signaling.
pyroptosis has been proposed as a potential pathogenic mechanism underlying
EZH2-STAT3 signaling pathway regulates GSDMD-mediated pyroptosis in glioblastoma.
pyroptosis in GBM through STAT3, and pyroptosis could potentially be targeted
Xihuang pill triggers dual gasdermin-mediated pyroptosis in glioma-associated endothelial cells via AMPK inhibition.
Pyroptosis was evaluated using optical microscopy, scanning electron microscopy, Hoechst
Evodiamine inhibits NLRP3 inflammasome-mediated microglial pyroptosis and promotes remyelination via SLC2A4-regulated autophagy.
pyroptosis, a pro-inflammatory type of cell death, in multiple
Perspectives on the mechanism of pyroptosis after intracerebral hemorrhage.
pyroptosis after ICH. Pyroptosis can be inhibited by directly targeting
Phillyrin prevents sepsis-induced acute lung injury through inhibiting the NLRP3/caspase-1/GSDMD-dependent pyroptosis signaling pathway.
pyroptosis by preventing the activation of the pyroptosis signaling pathway
Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3-mediated vascular smooth muscle cell pyroptosis in chronic kidney disease.
pyroptosis, and VC under CKD conditions. During mouse vascular smooth
HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model.
pyroptosis. The pyroptosis in cells of brain tissue was significantly
Extracellular vesicles of ADSCs inhibit ischemic stroke-induced pyroptosis through Gbp3 regulation: A role for the NLRP3/GSDMD signaling pathway.
Pyroptosis is a recently identified kind of programmed cell death
TLR4 aggravates microglial pyroptosis by promoting DDX3X-mediated NLRP3 inflammasome activation via JAK2/STAT1 pathway after spinal cord injury.
pyroptosis is crucial for the inflammatory response during secondary spinal
Using Blood-Based Biomarkers to Facilitate the Diagnosis of Alzheimer's Disease: Insights from a Novel Pyroptosis-Associated Molecular Signature Model.
pyroptosis in the advancement of AD. Yet, the precise role
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice.
pyroptosis and neuroinflammation with excess microglial activation are widely involved
Synthetic lethality of combined ULK1 defection and p53 restoration induce pyroptosis by directly upregulating GSDME transcription and cleavage activation through ROS/NLRP3 signaling.
pyroptosis. Mechanistically, p53 promote pyroptosis initiation by directly mediating GSDME
Inhibition of histone deacetylase 6 activity mitigates neurological impairment and post-hemorrhagic hydrocephalus after intraventricular hemorrhage by modulating pyroptosis and autophagy pathways.
pyroptosis is characterized by neuronal lysis and destruction, along with
Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation.
pyroptosis-related markers on microglia specifically. Notably, pyroptosis marker (caspase
Pyroptosis in acute pancreatitis and its therapeutic regulation.
pyroptosis has been implicated in AP. Therefore, the pyroptosis-related
Ticagrelor alleviates neuroinflammation after traumatic brain injury by inhibiting NLRP3 inflammasome-mediated pyroptosis.
Pyroptosis is a key driver of neuroinflammatory responses, and inhibiting
Proanthocyanidins alleviate acute alcohol liver injury by inhibiting pyroptosis via inhibiting the ROS-MLKL-CTSB-NLRP3 pathway.
Pyroptosis is a novel type of programmed cell death that