25 results for “tau”. Showing 25 of 39,449.
Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model.
tau protein, tau fibrils, and tau oligomers, would induce similar
Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy.
tau antibody. As tau transgenic mice accumulated insoluble tau in the brain
Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials.
tau, tau immunotherapy, tau aggregation inhibitors, and targeting production of tau
Tau Acetylation in Entorhinal Cortex Induces its Chronic Hippocampal Propagation and Cognitive Deficits in Mice.
tau (AAV-Tau-4Q), the non-acetylation tau mutant (AAV-Tau
Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain.
tau aggregates may be an underlying cause of Braak tau
Pre-synaptic C-terminal truncated tau is released from cortical synapses in Alzheimer's disease.
tau. Potassium-induced depolarization demonstrates release of tau and tau
Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
tau amyloid filaments from human brain revealed that distinct tau
iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death.
tau in the form of caspase-cleaved tau, phospho-tau
Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
tau-PSR). The direct effect of tau-PSR byproducts on tau
Targeted autophagic clearance of Tau protects against Alzheimer's disease through amelioration of Tau-mediated lysosomal stress.
Tau with Tau-specific autophagy degrader might be feasible. Methods
Tau from SPAM Transgenic Mice Exhibit Potent Strain-Specific Prion-Like Seeding Properties Characteristic of Human Neurodegenerative Diseases.
tau protein into neurofibrillary tangles. Despite extensive studies on tau
Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration.
tau shows lack of correlation with CSF total-tau. Recent
Spreading of Tau Protein Does Not Depend on Aggregation Propensity.
Tau. The nature of Tau and the cellular mechanisms of Tau
Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice.
tau and several phosphorylated tau species in the insoluble fraction
Bridging Integrator-1 protein loss in Alzheimer's disease promotes synaptic tau accumulation and disrupts tau release.
tau. Tau is normally a highly soluble cytoplasmic protein, but in Alzheimer
Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo.
Tau-pathology. Tau pathology was thereby also induced by aggregated
Ganglioside sialylation modulates tau internalization and pathology spread.
tau aggregates by neurons is integral to the propagation of tau
Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains.
tau) and three (3R tau) repeat tau isoforms whereas cases
P62 accumulates through neuroanatomical circuits in response to tauopathy propagation.
tau (EC-Tau) mice where tau pathology progresses in time
Trem2 deletion enhances tau dispersion and pathology through microglia exosomes.
tau levels, and feature enhanced tau-seeding capacity in a tau
Tau<sup>P301L</sup> disengages from the proteosome core complex and neurogranin coincident with enhanced neuronal network excitability.
tau (tau WT ) and P301L mutant 0N4R tau (tau P301L
Spreading of Alzheimer tau seeds is enhanced by aging and template matching with limited impact of amyloid-β.
tau sequence replacing mouse tau, template matching enhanced neuritic tau
Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography.
tau (p-tau) biomarkers has raised questions about their preferential
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease.
tau protein in the form of abnormally hyperphosphorylated tau (PHF-tau
CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease.
tau, such as CSF total tau and phosphorylated tau-181 and tau