25 results for “type-2-diabetes”. Showing 25 of 39,449.
Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes.
type-2 diabetes have increased plasma levels of ANXA1 when
Can Alzheimer's Disease Be Secondary to Type-2 Diabetes Mellitus?
diabetes mellitus. Type-2 diabetes mellitus and its relationship to other
GLP1 Receptor Agonists-Effects beyond Obesity and Diabetes.
type-2 diabetes and obesity. Drugs of this class, the bioavailability
Probucol prevents blood-brain barrier dysfunction and cognitive decline in mice maintained on pro-diabetic diet.
type-2 diabetes. Our previous studies demonstrated that selected anti
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
type-2 diabetes remain unresolved. Using a combination of transcriptomics
Regulation of therapeutic protein release in response to circadian biomarkers.
potential as an experimental cell therapy for obesity-dependent type-2 diabetes.
A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes
Superoxide-producing lipoprotein fraction from Stevia leaves: definition of specific activity.
role in type-2 diabetes by means of adrenaline oxidation mechanism.
Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'.
Type-2 diabetes, fractionation hinged on binding to phosphatidylinositol trisphosphate
Neuroprotective Potential of Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors in Type 2 Diabetes: A Narrative Review.
-2 (SGLT2) inhibitors are now at the center of a compelling new research question: do their benefits extend to the brain? As dementia rates climb globally, this can be linked
Indole-3-propionic acid links gut dysfunction to diabetic retinopathy: a biomarker and novel therapeutic approach.
-2) dependent or independent Trp absorption in a model of type 2 diabetes
Empagliflozin Ameliorates Type 2 Diabetes-Induced Ultrastructural Remodeling of the Neurovascular Unit and Neuroglia in the Female
type 2 diabetic db/db female mice. Herein, we tested whether the SGLT-2
Empagliflozin Attenuates High-Glucose-Induced Astrocyte Activation and Inflammation via NF-κB Pathway.
-2 (SGLT2) inhibitors regulate blood glucose levels in patients with type 2 diabetes
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.
Type 2 diabetes mellitus (T2DM) increases the risk for Alzheimer's disease (AD). Human AD brains show reduced glucose metabolism as measured by [18F]fluoro-2
Sodium-Glucose Cotransporter-2 Inhibitors, Dulaglutide, and Risk for Dementia : A Population-Based Cohort Study.
-2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may have neuroprotective effects in patients with type 2 diabetes
Decreasing the TORC on memory CD8 T‐cell formation
-2 withdrawal in vitro.4 Finally, the authors showed that in vivo administration of the drugs metformin (which activates AMPK and FAO and is therapeutic for type II diabetes
Comparative effectiveness of SGLT2 inhibitors and GLP-1 receptor agonists in preventing Alzheimer's disease, vascular dementia, and other dementia types among patients with type 2 diabetes.
Type 2 diabetes mellitus (T2DM) is associated with an elevated risk of dementia, including Alzheimer's disease (AD) and vascular dementia (VaD). While sodium-glucose cotransporter-2
Inflammatory proteins associated with Alzheimer's disease reduced by a GLP1 receptor agonist: a post hoc analysis of the EXSCEL randomized placebo controlled trial.
type 2 diabetes mellitus. 4,979 proteins were measured (Somascan V0.4) on baseline and 1-year plasma samples of 3,973 participants. C-reactive protein (CRP), ficolin-2
Regulatory Roles of IGF2R in Insulin Secretion and Adaptive β-Cell Proliferation.
type 2 diabetes. Taken together, these data point to IGF2R as an important regulator of insulin secretion, cell proliferation, and autophagy in mammalian β-cells. ARTICLE HIGHLIGHTS: The significance
[(131)I]N-(6-amino-2,2,4-trimethylhexyl)-2-[(5-iodo(3-pyridyl))carbonylamino]-3-(2-napthyl)propanamide.
type 2 (VMAT2) in the pancreas (5-7). Although the VMAT2 has been used extensively for PET imaging of the brain in individuals suffering from Parkinson’s disease
Methionine restriction alleviates diabetes-associated cognitive impairment via activation of FGF21.
type 2 diabetes. Notably, MR significantly improved working as well as long-term memory in db/db mice, accompanied by increased PSD-95 level and reduced neuroinflammatory factors, malondialdehyde
AZGP1 Aggravates Macrophage M1 Polarization and Pyroptosis in Periodontitis.
type 2 diabetes mellitus (T2DM). Accumulating evidence highlights the intricate involvement of macrophage-mediated inflammation in the pathogenesis of periodontitis under both normal and T2DM conditions. However, the underlying mechanism
Can maternal metformin protect the developing fetal brain?
type 2 diabetes mellitus (n=40 in each group) or gestational diabetes mellitus. Fetal neuronally derived extracellular vesicles were purified from maternal serum collected at 24 to 30 weeks. Sirtuin
SGLT2 and DPP4 inhibitors improve Alzheimer's disease-like pathology and cognitive function through distinct mechanisms in a T2D-AD mouse model.
type 2 diabetes mellitus (T2D) share common features, including insulin resistance. Brain insulin resistance has been implicated as a key factor in the pathogenesis of AD. Recent studies have demonstrated
Astragaloside IV Exhibited Antidiabetic Effects by Improving Glucose Metabolism, Repairing Damaged Gut Barrier and Regulating Intestinal Microbiota.
type 2 diabetes mellitus (T2DM). This study was aimed to figure out its antidiabetic mechanisms. The db/db mice were treated with AS-IV, and the metabolism phenotype and epithelial barrier