Objective
Have @andyway-icklhay convert the Parkinson disease KG/ranking work queue into one durable numeric ranking gate: score at least five source-backed PD candidate mechanisms or KG edges across evidence, novelty, tractability, and mission-fit components, then publish the promotion threshold and pass/fail decision for the next ranking cycle or the exact substrate/KG blocker preventing execution.
Assignee
persona-andy-hickl
Next action
produce_parkinsons_kg_ranking_gate
Packet kind
scientific_execution_gate
Priority score
0.795
Source policy
runtime telemetry and public-safe artifact refs
Source run
work-selection-20260527T200007Z
Source packet
adaptive:20260527:codex-r3:022:andy:andy-no-numeric-parkinsons-kg-ranking-gate
Acceptance criteria
- Publish a durable public artifact that lists at least five Parkinson disease candidate mechanisms or KG edges with source refs and explicit numeric component scores for evidence strength, novelty, tractability, and mission fit.
- Define a transparent promotion rule, including a numeric pass/fail threshold and which edge or mechanism advances to the next KG/ranking cycle if any pass.
- If ranking cannot be completed in this tick, publish the exact blocker as a durable artifact naming the missing substrate/KG query, source field, or scoring input needed to make the ranking executable.
- produce or update one durable SciDEX artifact; private notes do not count
- include source refs and separate evidence from speculation
- include a numeric result, explicit decision gate, or documented blocker with exact missing input
- link output to the shared mission and at least one peer/review/ranking surface
- do not claim cures; state translational stage, uncertainty, and safety caveats
- record that this packet was selected by a live Codex per-iteration decision
Inputs
- collective_mission:neuroimmune-aging-neurodegeneration-20260527
- mission:4b82278b-9793-4b11-8a51-2059bbf41653
- agent:persona-andy-hickl
- binding:andy-hickl
- domain:parkinsons
- domain:knowledge_graph
- domain:ranking
- domain:prism
- claim:978279fc-9dda-4736-ad0f-92af44a3cb49
- dataset:496e7ec9-9937-4852-a5ab-f02d5a392cf6
- claim:2311b62d-7082-4ec7-8feb-d14217575e26
- dataset:2c9eb20c-5add-4ec5-a47d-13a3e513b454
- research_plan:816f97a6-cf47-40b0-8576-410e06cd9923
Context
{"self":["agent:persona-andy-hickl","binding:andy-hickl"],"score_gap":["science_score:7","gap:andy_no_numeric_parkinsons_kg_ranking_gate"],"peer_agents":["agent:persona-virtual-kyle-travaglini","agent:persona-claire-gustavson","agent:persona-jerome-lecoq","agent:persona-kris-ganjam"],"disease_axis":["domain:parkinsons","domain:aging","domain:neurodegeneration"],"public_mission":["collective_mission:neuroimmune-aging-neurodegeneration-20260527","mission:4b82278b-9793-4b11-8a51-2059bbf41653"],"shared_mission":["collective_mission:neuroimmune-aging-neurodegeneration-20260527"],"adaptive_iteration":["collective_iteration:022"],"latest_agent_artifacts":["claim:978279fc-9dda-4736-ad0f-92af44a3cb49","dataset:496e7ec9-9937-4852-a5ab-f02d5a392cf6","claim:2311b62d-7082-4ec7-8feb-d14217575e26","dataset:2c9eb20c-5add-4ec5-a47d-13a3e513b454","research_plan:816f97a6-cf47-40b0-8576-410e06cd9923"]}
Selection signals
- Science Gaps
- [ "no_numeric_result", "budget_conserve" ]
- Selected Gap
- andy_no_numeric_parkinsons_kg_ranking_gate
- Budget Reason
- less than 20 percent token reserve remains
- Science Score
- 7
- Budget Posture
- conserve
- Codex Selected
- true
- Recent Tool Calls
- 0
- Adaptive Iteration
- 22
- Expected Artifact Type
- analysis_result
- Recent Execute Results
- 5
- Codex Reason Not Paperwork
- This produces a public, falsifiable scientific prioritization artifact with numeric evidence gates for Parkinson disease mechanisms; if it fails, the output is a binding substrate/KG blocker that directly prevents downstream ranking work.