Details
- scope
- vip-interneurons
- claim_text
- Previously, loss of the <i>Tsc1</i> gene, which results in hyperactive mTOR, was shown to affect the function and molecular properties of GABAergic cortical interneurons (CINs) derived from the medial ganglionic eminence.
- section_id
- section_08
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-08-in-vivo-behavior
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- Previously, loss of the <i>Tsc1</i> gene, which results in hyperactive mTOR, was shown to affect the function and molecular properties of GABAergic cortical interneurons (CINs) derived from the medial ganglionic eminence.
- section_title
- In Vivo Function During Behavior
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- unevaluated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-08-in-vivo-behavior
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.3390/cells13010052", "pmid": "38201256", "tags": [ "disease_R4" ], "year": "2023", "claim": "Previously, loss of the <i>Tsc1</i> gene, which results in hyperactive mTOR, was shown to affect the function and molecular properties of GABAergic cortical interneurons (CINs) derived from the medial ganglionic eminence.", "pmcid": "PMC10777938", "round": 4, "title": "<i>Tsc1</i> Loss in VIP-Lineage Cortical Interneurons Results in More VIP+ Interneurons and Enhanced Excitability.", "authors": "Hu JS, Malik R, Sohal VS, Rubenstein JL, Vogt D.", "journal": "", "citation": "Hu JS, Malik R, Sohal VS, Rubenstein JL, Vogt D. (2023). . 10.3390/cells13010052", "cite_key": "Hu2023", "effect_size": null, "text_access": "fulltext", "citedByCount": 1, "isOpenAccess": "Y", "evidence_type": "circuit_function", "linked_topics": [ "disinhibition_circuit", "disease_models" ], "_source_cluster": "cluster_07_in_vivo_function", "relevance_score": 8.6, "replication_status": null, "_source_cluster_index": 146, "claim_source_sentence": "Previously, loss of the <i>Tsc1</i> gene, which results in hyperactive mTOR, was shown to affect the function and molecular properties of GABAergic cortical interneurons (CINs) derived from the medial ganglionic eminence." }- source_refs
[ "paper:paper-0352793d2854" ]
- evidence_refs
[ { "ref": "paper:paper-0352793d2854" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }