Details
- scope
- mouse C2 barrel column of primary somatosensory cortex (S1), acute slices, multiple whole-cell paired recordings
- claim_text
- In mouse C2 barrel column, paired recordings across all cortical layers reveal layer-specific E→E connectivity, with presynaptic layer 4 neurons providing the strongest excitatory influence on the column.
- section_id
- section_04
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- effect_size
- Layer-specific connection probabilities and amplitudes (full matrix in paper).
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- source_kind
- review_finding
- source_path
- evidence/section_04_evidence_package.json
- study_system
- mouse C2 barrel column of primary somatosensory cortex (S1), acute slices, multiple whole-cell paired recordings
- section_title
- 4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
- evidence_summary
- Multiple simultaneous whole-cell paired recordings in acute slices of C2 barrel column of mouse S1.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- raw_fields
{ "n": 0, "doi": "10.1016/j.neuron.2008.12.020", "claim": "In mouse C2 barrel column, paired recordings across all cortical layers reveal layer-specific E→E connectivity, with presynaptic layer 4 neurons providing the strongest excitatory influence on the column.", "cite_key": "Lefort2009", "evidence": "Multiple simultaneous whole-cell paired recordings in acute slices of C2 barrel column of mouse S1.", "effect_size": "Layer-specific connection probabilities and amplitudes (full matrix in paper).", "text_access": "abstract_only", "study_system": "mouse C2 barrel column of primary somatosensory cortex (S1), acute slices, multiple whole-cell paired recordings", "argument_role": "supporting", "replication_status": "independently_replicated", "claim_source_sentence": "Synaptic connectivity depended strongly upon somatic laminar location of both presynaptic and postsynaptic neurons, providing definitive evidence for layer-specific signaling pathways. The strongest excitatory influence upon the cortical column was provided by presynaptic layer 4 neurons.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1093/cercor/bhx094", "10.1016/j.celrep.2018.08.038" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-bdc020492b80" ]
- source_span
Synaptic connectivity depended strongly upon somatic laminar location of both presynaptic and postsynaptic neurons, providing definitive evidence for layer-specific signaling pathways. The strongest excitatory influence upon the cortical column was provided by presynaptic layer 4 neurons.
- evidence_refs
[ { "ref": "paper:paper-bdc020492b80" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }