Details

scope
vip-interneurons
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-08-in-vivo-behavior
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
section_title
In Vivo Function During Behavior
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
unevaluated
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-08-in-vivo-behavior
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
Cortical interneurons express high levels of opioid receptors, positioning opioid signaling as a critical regulator of inhibitory transmission; however, we lack a complete understanding of how classical opioid receptor systems regulate prefrontal cortex (PFC) microcircuitry.
raw_fields
{
  "n": null,
  "doi": "10.1523/jneurosci.1963-24.2025",
  "pmid": "40393805",
  "tags": [
    "sweep_R3"
  ],
  "year": "2025",
  "claim": "Cortical interneurons express high levels of opioid receptors, positioning opioid signaling as a critical regulator of inhibitory transmission; however, we lack a complete understanding of how classical opioid receptor systems regulate prefrontal cortex (PFC) microcircuitry.",
  "pmcid": "PMC12225597",
  "round": 3,
  "title": "Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms.",
  "authors": "Cole RH, Allichon MC, Joffe ME.",
  "journal": "",
  "citation": "Cole RH, Allichon MC, Joffe ME. (2025). . 10.1523/jneurosci.1963-24.2025",
  "cite_key": "Cole2025",
  "effect_size": null,
  "text_access": "fulltext",
  "citedByCount": 1,
  "isOpenAccess": "N",
  "evidence_type": "in_vivo_function",
  "linked_topics": [
    "prefrontal_VIP"
  ],
  "_source_cluster": "cluster_07_in_vivo_function",
  "relevance_score": 5.1,
  "replication_status": null,
  "_source_cluster_index": 118,
  "claim_source_sentence": "Cortical interneurons express high levels of opioid receptors, positioning opioid signaling as a critical regulator of inhibitory transmission; however, we lack a complete understanding of how classical opioid receptor systems regulate prefrontal cortex (PFC) microcircuitry."
}
source_refs
[
  "paper:paper-208bbf2a3ba6"
]
source_span
Cortical interneurons express high levels of opioid receptors, positioning opioid signaling as a critical regulator of inhibitory transmission; however, we lack a complete understanding of how classical opioid receptor systems regulate prefrontal cortex (PFC) microcircuitry.
evidence_refs
[
  {
    "ref": "paper:paper-208bbf2a3ba6"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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