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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Neuroimmune Dysfunction in Frontotemporal Dementia
Ftd["Ftd"] Ftld["Ftld"] -->|"associated with"| Ftd["Ftd"] Als["Als"] -->|"associated
Read more → - Frontotemporal Dementia (FTD) Mechanistic Pathway
FTD ### Autosomal Dominant FTD Approximately 30-40% of FTD cases
Read more → - Ion Channel Dysfunction in Frontotemporal Dementia
FTD (bvFTD), primary progressive aphasia (PPA) variants, and FTD with
Read more → - Corticosteroids in FTD Trial
Ftd["Corticosteroids in FTD Trial"] Ftd["Corticosteroids in FTD Trial
Read more → - TREM2 in Frontotemporal Dementia
FTD["Frontotemporal Dementia Progression"] TAU --> FTD NEURON --> FTD style TREM2
Read more →
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Related hypotheses
- CYP46A1 Suppression for Tau-Mediated Neurodegeneration
central nervous system. In frontotemporal dementia (FTD) and related tauopathies, pathological CYP46A1 hyperactivity disrupts neuronal ... cholesterol equilibrium. CYP46A1 overexp…
- Astrocyte-Neuron Metabolic Coupling Failure Precedes Neurodegeneration in FTD-GRN
pathogenesis of frontotemporal dementia with GRN mutations (FTD-GRN) involves a complex interplay between progranulin ... neuroinflammation, lysosomal function, and cellular metab…
- APOE4 Induces Region-Specific Microglial Senescence Driving Frontal Cortex Neurodegeneration
Novel senescence mechanism linking APOE4 genetics to FTD-like neurodegeneration. Framed more explicitly, the hypothesis ... strongest genetic risk factor for AD and FTD. [PMID:353…
- Nuclear TDP-43 Depletion Drives Synaptic Splicing Dysregulation in ALS-FTD
Depletion Drives Synaptic Splicing Dysregulation in ALS-FTD starts from the claim that modulating TARDBP ... Depletion Drives Synaptic Splicing Dysregulation in ALS-FTD starts fro…
- TFEB Nuclear Translocation to Reset Lysosomal-Hypoxia Axis
Paget disease of bone (PDB), frontotemporal dementia (FTD), and amyotrophic lateral sclerosis (ALS). The connection ... improving motor neuron survival. **Frontotemporal Dementia …