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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- HIF1A Gene - Hypoxia Inducible Factor 1 Subunit Alpha
HIF1A["HIF1A"] IDH2["IDH2"] -->|"associated with"| HIF1A["HIF1A"] USP22["USP22
Read more → - HIF-1α Protein
HIF1A["HIF1A"] IDH2["IDH2"] -->|"associated with"| HIF1A["HIF1A"] USP22["USP22
Read more → - HIF-1α (Hypoxia-Inducible Factor 1-Alpha)
HIF1A HIF1A -->|"regulates"| VEGF HIF1A -->|"activates"| BNIP3 style HIF1A fill
Read more → - VEGF (Vascular Endothelial Growth Factor)
HIF1A["HIF1A Hypoxia-Inducible Factor"] VEGF["VEGF Vascular Endothelial Growth
Read more → - BNIP3 Gene
HIF1A["HIF1A"] HIF1A -->|"activates"| BNIP3 APOPTOSIS["APOPTOSIS"] APOPTOSIS -->|"activates"| BNIP3
Read more →
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Related hypotheses
- HIF1A stabilization lowers the activation threshold of circadian-disrupted microglia
stabilization of hypoxia-inducible factor 1-alpha (HIF1A) in microglia following circadian disruption, leading ... metabolically primed inflammatory state. Under normoxic conditio…
- Dysregulated microglial glycolysis via HIF1α activation shifts the balance from neuroprotective surveillance to complement-mediated synapse engulfment
engulfment starts from the claim that modulating HIF1A, LDHA, LDHB, PKM2, TREM2, AMPK/mTOR within ... engulfment starts from the claim that modulating HIF1A, LDHA, LDHB, PKM2, TRE…
- Perinatal Hypoxia-Primed Microglia Targeting
Targeting starts from the claim that modulating HIF1A, NFKB1 within the disease context of Alzheimer ... Targeting starts from the claim that modulating HIF1A, NFKB1 within the di…
- Hypothesis 4: Metabolic Coupling via Lactate-Shuttling Collapse
enzymes **PFKM**, **ENO2**, and **ALDOA**, and with **HIF1A**, the master hypoxia transcription factor. The **LDHA ... HIF1A** regulatory axis is directly relevant to VCP-mutant a…
- Lactate-HCAR1 signaling maintains a self-reinforcing glycolytic priming loop
inhibit prolyl hydroxylases and thereby stabilize HIF1A, providing a possible link to glycolytic feedback. [PMID ... inhibit prolyl hydroxylases and thereby stabilize HIF1A, provi…