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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- IL1B Gene - Interleukin 1 Beta
IL1B Pro_IL1B -->|"processed to"| Mature_IL1B Mature_IL1B -->|"is"| IL1B
Read more → - IL1B — Interleukin-1 Beta
IL1B["IL1B"] Berberine["Berberine"] -.->|"inhibits"| IL1B["IL1B"] Cyclosporine_A["Cyclosporine
Read more → - Validated Hypothesis: Mitochondrial DAMPs-Driven AIM2 Inflammasome Activation in Neurodegeneration
IL1B, PYCARD](https://www.ncbi.nlm.nih.gov/gene/?term=AIM2, CASP1, IL1B, PYCARD) - [UniProt: AIM2
Read more → - Validated Hypothesis: Gut Microbiome Remodeling to Prevent Systemic NLRP3 Priming in Neurodegeneration
IL1B, PYCARD](https://www.ncbi.nlm.nih.gov/gene/?term=NLRP3, CASP1, IL1B, PYCARD) - [UniProt: NLRP3
Read more → - Validated Hypothesis: Microglial AIM2 Inflammasome as the Primary Driver of TDP-43 Proteinopathy Neuroinflammation in ALS/FTD
IL1B, PYCARD, TARDBP](https://www.ncbi.nlm.nih.gov/gene/?term=AIM2, CASP1, IL1B, PYCARD, TARDBP
Read more →
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Related hypotheses
- Blood Monocyte Epigenetic Signature as Surrogate for Microglial Priming
claim that modulating Epigenetic landscape (TLR4, NLRP3, IL1B regulatory regions) within the disease context ... claim that modulating Epigenetic landscape (TLR4, NLRP3, IL1B regu…
- Combined NAMPT-Alectinib Targeting of SASP-Complement Cascade
claim that modulating NAMPT, SIRT1, C1QA/C1QB/C1QC, IL1B within the disease context of neuroinflammation can redirect ... claim that modulating NAMPT, SIRT1, C1QA/C1QB/C1QC, IL1B …
- Selectively Inhibit Maladaptive AQP4-Driven Astrocyte-Microglia Inflammatory Signaling in Parkinsonian Injury
from the claim that modulating AQP4, NFKB1, IL1B, TNF within the disease context of neurodegeneration ... from the claim that modulating AQP4, NFKB1, IL1B, TNF within the disease …
- Gut Microbiome Remodeling to Prevent Systemic NLRP3 Priming in Neurodegeneration
from the claim that modulating NLRP3, CASP1, IL1B, PYCARD within the disease context of neurodegeneration ... from the claim that modulating NLRP3, CASP1, IL1B, PYCARD within the …
- Astrocyte-Intrinsic NLRP3 Inflammasome Activation by Alpha-Synuclein Aggregates Drives Non-Cell-Autonomous Neurodegeneration
from the claim that modulating NLRP3, CASP1, IL1B, PYCARD within the disease context of neurodegeneration ... from the claim that modulating NLRP3, CASP1, IL1B, PYCARD within the …