25 results for “Cell Reports”. Showing 25 of 39,449.
Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters
cell reporter assays. The resulting measurement of reporter expression is accurate
Multiplex profiling of developmental enhancers with quantitative, single-cell expression reporters
cell reporter assays, resulting in accurate measurement of reporter expression
A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms.
cell-based reporter that captures both aggregation and the resulting
Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types
Cell Reports 40, 111176; August 9, 2022) After publication, the text
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.
reporter cell lines in a series of CRISPR-Cas9 loss
HCAR2 is a novel receptor for heme.
reporter cell assay and direct interaction analyses via surface plasmon
Clearance of β-amyloid mediated by autophagy is enhanced by MTORC1 inhibition but not AMPK activation in APP/PSEN1 astrocytes.
reported cells, similar to our previous findings in neurons. Our data
Author response: A simple method for generating high-resolution maps of genome-wide protein binding
Cell Reports 2:1025–1035. https://doi.org/10.1016/j.celrep.2012.08.034 Google Scholar
Author response: A simple method for generating high-resolution maps of genome-wide protein binding
Cell Reports 2:1025–1035. https://doi.org/10.1016/j.celrep.2012.08.034 Google Scholar
The Dichotomous Nature of AZ5104 (an EGFR Inhibitor) Towards RORγ and RORγT.
reporter cell line and used it to screen a library
Preterm human milk contains a large pool of latent TGF-β, which can be activated by exogenous neuraminidase.
reporter cells and in murine intestinal tissue explants. TGF-β1, TGF-β2, TGF-β3, and various
Human iPSC-derived hippocampal spheroids: An innovative tool for stratifying Alzheimer disease patient-specific cellular phenotypes and developing therapies.
Cell Reports. 2020 Jul 14;15(1):256-273. doi: 10.1016/j.stemcr.2020.06.001
γ-Aminobutyric acid type A (GABAA) receptor activation modulates tau phosphorylation.
cell reporter system based on protein-fragment complementation assay to study
Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway.
reporter cell line, compounds that activate PPARγ activity were identified
AMPK activation does not enhance autophagy in neurons in contrast to MTORC1 inhibition: different impact on β-amyloid clearance.
reported cells, lacking a direct effect on autophagy-dependent amyloidosis.Abbreviations
A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality
cell types in the brain and facilitating the study of their function. Here, we report
A suite of transgenic driver and reporter mouse lines with enhanced brain cell type targeting and functionality
reporter transgenic mouse lines, including 23 new driver lines targeting a variety of cortical and subcortical cell
Author response: SMAD4 and TGFβ are architects of inverse genetic programs during fate determination of antiviral CTLs
cells, investigators reported modified effector responses after T cell activation
Bioinformatics analysis indicates that microRNA‑628‑5p overexpression may alleviate Alzheimer's disease by targeting TYROBP.
cells. Luciferase reporter assay and RNA interference were utilized to verify
Integration of multiple epigenomic marks improves prediction of variant impact in saturation mutagenesis reporter assay
reporter assay (MPRA) in relevant cell lines. Reporter expression was measured
Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD.
cell types is lacking. Here, we report a high-resolution
A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types.
cell populations. We report evaluation of fifteen new transgenic driver
A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types.
cell populations. We report creation and evaluation of fifteen transgenic
Idiopathic giant cell myocarditis--a case report and review of literature.
cells. We hereby report a case of IGCM in a 72 year
Adapting Drosophila melanogaster Cell Lines to Serum-Free Culture Conditions.
cell proliferation. Here, we report a serum-free culture condition