25 results for “Cellular Neurobiology”. Showing 25 of 39,449.
T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice.
Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan. (3)Laboratory
Bidirectional regulation by "star forces": Ionotropic astrocyte's optical stimulation suppresses synaptic plasticity, metabotropic one strikes back.
Cellular Neurobiology of Learning, Institute of Higher Nervous Activity and Neurophysiology
A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism.
neurobiological bases have remained elusive, resulting in an intense debate around the cellular
Principles of Optogenetic Methods and Their Application to Cardiac Experimental Systems.
cellular excitability with millisecond precision. This review summarizes optogenetic approaches, using examples from neurobiological
APOE is a major susceptibility gene for Alzheimer's disease.
neurobiology. As apoE is not known to be expressed in neurons, its relationship with cellular
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA. (5)Department of Neurobiology
Lipid accumulation drives cellular senescence in dopaminergic neurons.
cellular senescence in dopaminergic neurons. Russo T(1)(2), Riessland M(1)(2). Author information: (1)Department of Neurobiology
The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease.
neurobiological and systems neurophysiological levels. By engaging distinct pre- and postsynaptic structures within the stimulated neural network, it directly or indirectly influences various cellular
New Developments in Sleep Research: Molecular Genetics, Gene Expression, and Systems Neurobiology
Understanding the mechanisms that underlie the control of sleep and
Running from Stress: Neurobiological Mechanisms of Exercise-Induced Stress Resilience.
cellular bioenergetics, stimulating the processes responsible for the removal of damaged organelles and molecules, and attenuating inflammation processes. Regular physical activity brings another important benefit: increased stress robustness. The evidence
Glucagon-like peptide-1 receptor agonists for major neurocognitive disorders.
neurobiological processes. In vitro and animal studies have revealed promising signals of neuroprotection, with preliminary supportive evidence emerging from recent pharmacoepidemiological investigations and clinical trials. In this article, we comprehensively
Interneuron Dysfunction in Syndromic Autism: Recent Advances.
cellular elements that control hyperexcitability in the brain, and interneuron dysfunction can cause pathological hyperexcitability linked to seizure susceptibility or epilepsy. This review summarizes some of the recent advances that
Therapeutic Potential of Vital Transcription Factors in Alzheimer's and Parkinson's Disease With Particular Emphasis on Transcription Factor EB Mediated Autophagy.
cellular organelles due to impairment in the autophagy pathway. This dysfunction in autophagy characterized by the accumulation of toxic protein aggregates leads to a progressive loss in structural integrity/functionality
Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine.
neurobiology. It is widely assumed that CASM involves the same conjugation of ATG8 to PE, but this has not been formally tested. Here, we discover that all ATG8s can also
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients.
Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA. (6)Neural Aging Laboratory, Institute of Molecular Biology, CMBI, Leopold-Franzens-University Innsbruck, Tyrol, Austria. (7)Department
Integrated Profiling of DEHP-Induced Hippocampal Neurotoxicity in Adult Female Rats Based on Transcriptomic and Neurobiological Analyses.
Di-2-ethylhexyl phthalate (DEHP) is a widely used plasticizer
Genomic Views of Transcriptional Enhancers: Essential Determinants of Cellular Identity and Activity-Dependent Responses in the CNS.
UNLABELLED: Sprinkled throughout the genome are a million regulatory sequences
Cortical evolution: judge the brain by its cover.
neurobiology, coupled with those in genetics, including adaptive protein evolution via gene duplications and the emergence of novel regulatory elements, can provide insights into the evolutionary mechanisms culminating
Proteomic landscape of Alzheimer's disease: emerging technologies, advances and insights (2021 - 2025).
Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Junmin.peng@stjude.org. (#)Contributed equally The advancements of proteomics technologies are shaping Alzheimer's disease (AD) research, revealing new molecular insights
Frontotemporal Dementia: A Clinical Review.
Neurobiologically, these diseases can be regarded as "molecular nexopathies," a paradigm for selective targeting and destruction of brain networks by pathogenic proteins. Mutations in three major genes collectively account
From geroscience to precision geromedicine: Understanding and managing aging.
Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore, Singapore; Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Optogenetic approaches for neural tissue regeneration: A review of basic optogenetic principles and target cells for therapy.
cellular targets for optogenetics, including neurons, astrocytes, microglia, and Schwann cells. Utilizing specific promoters for opsin expression in these cells is essential for achieving precise and efficient stimulation. Research
Central Role of Hypothalamic Circuits for Acupuncture's Anti-Parkinsonian Effects.
neurobiological basis of the effectiveness of acupuncture in treating diseases of the central nervous system has remained elusive. Here, using an established model of acupuncture treatment in Parkinson's disease
Consistent genes associated with structural changes in clinical Alzheimer's disease spectrum.
neurobiological and pathogenic substrates underlying this structural atrophy across the AD spectrum remain largely understood. METHODS: In this study, we obtained structural MRI data from ADNI datasets, including 83 participants
The role of exercise in enhancing brain and cerebrovascular health via the bone-brain axis: implications for surgical and clinical interventions.
cellular mechanisms underlying the bone–brain axis, with a particular focus on exercise-induced pathways. Physical activity stimulates the secretion of myogenic and neuromodulatory mediators including brain-derived neurotrophic factor