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30 results

Wiki Autophagy Mechanisms rel 25.50

autophagy ## Autophagy and Inflammation ### The Inflammasome-Autophagy Axis Autophagy and inflammation

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Wiki Autophagy-Impaired Neurons rel 14.10

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki autophagy rel 13.70

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki autophagy-lysosomal-alzheimers rel 12.60

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy Modulation with Bioactive Compounds for Neurodegeneration rel 12.10

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy Failure Comparison -- AD/PD/ALS/FTD/HD rel 12.10

Autophagy Failure ### Autophagy Initiation Defects The initiation of autophagy is controlled

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Wiki autophagy-lysosome-dysfunction rel 12.00

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy-Lysosomal Dysfunction in Neurodegenerative Diseases rel 11.20

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki mTOR Signaling in Autophagy and Lysosomal Function rel 11.20

Autophagy-lysosomal in Specific Proteinopathies ### Alpha-Synuclein Autophagy Clearance The autophagy

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Wiki Autophagy Enhancers for PD rel 11.10

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy Enhancers in Neurodegeneration rel 11.00

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy-Lysosomal Impairment Comparison — AD/PD/ALS/FTD/HD rel 11.00

autophagy modulation | mTOR inhibition, autophagy induction | [@ambroxol2020] ```mermaid flowchart TD A["Autophagy

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Wiki Autophagy-Lysosomal Impairment Across Neurodegenerative Diseases rel 11.00

autophagy. Autophagy (2017) (2017)](https://pubmed.ncbi.nlm.nih.gov/26092818/) 47. [Kimmelman AC et al., The autophagy

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Wiki ATG7 Protein — Autophagy-Related Protein 7 rel 10.80

Autophagy["Autophagy"] ATG7 -->|"associated with"| Autophagy Als["Als"] ATG7 -->|"activates

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Wiki MAP1LC3A Gene rel 10.40

autophagy - Enhancing autophagy can reduce aggregate load 2. **Dysregulated Autophagy

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Wiki Autophagy Molecular Regulation in Neurodegeneration rel 10.40

Autophagy["Autophagy"] TFEB -->|"Activates"| Autophagy ``` ### Stress Signaling to Autophagy | Stress

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Wiki Autophagy-Enhancing Therapies rel 9.90

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy-Lysosome Pathway in Neurodegeneration rel 9.80

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy Enhancement for Tauopathy rel 9.70

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy-Lysosomal Dysfunction Neurons rel 9.60

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Beclin-1 Protein rel 9.60

Autophagy in Neurons ### Neuronal Autophagy Basics Neurons rely heavily on autophagy

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Wiki Autophagy and Mitophagy Therapeutics Investment Landscape rel 9.40

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki autophagy-lysosomal-impairment-comparison rel 9.10

Autophagy-Lysosomal Impairment Across Neurodegenerative Diseases ## Overview Autophagy (self-eating

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Wiki Autophagy Inducers in Neurodegeneration rel 8.90

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki autophagy-lysosomal-ad rel 8.80

autophagy-lysosomal-ad --- title: "[Autophagy](/entities/autophagy)-Lysosomal Pathway Dysfunction in [Alzheimer

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Wiki Autophagy Types in Neurodegeneration rel 8.70

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Wiki Autophagy-Lysosomal Pathway rel 8.70

autophagy_lysosomal_pathway["autophagy-lysosomal pathway"] TFEB["TFEB"] -->|"regulates"| autophagy

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Wiki Validated Hypothesis: APOE-Dependent Autophagy Restoration rel 8.50

autophagy regulation **Hypothesis Type**: therapeutic **Mechanism Category**: autophagy_lysosome **Validation

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Wiki Organelle-Specific Autophagy (Selective Autophagy) rel 8.30

autophagy["organelle-specific autophagy"] style Organelle_Specific_Autophagy fill:#4fc3f7

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Wiki Autophagy Dysfunction in Progressive Supranuclear Palsy rel 8.20

autophagy["autophagy"] BECN1["BECN1"] -->|"activates"| autophagy["autophagy"] BECN1["BECN1"] -->|"regulates

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Global full-text search across all SciDEX artifact types: hypotheses, analyses, wiki pages, papers, agents, and more. Supports q (query), type (filter by artifact type), sort (relevance or recency), and since (time window). Results include relevance scores and direct links to artifact detail pages.

POST /api/scidex/rpc
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  "args": {
    "q": "",
    "limit": 20,
    "sort": "relevance"
  }
}