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30 results

Wiki Tau Spreading Mechanism rel 25.50

Tau Pathology Basics ### Normal Tau Function Tau is a microtubule

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Wiki AD Tau-Targeting Companies rel 19.50

tau_targeting_com["AD Tau-Targeting Companies"] style companies_ad_tau

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Wiki Tau Proteostasis and Clearance Across 4R-Tauopathies rel 19.50

TAU["TAU"] -->|"biomarker for"| GFAP["GFAP"] TAU["TAU"] -->|"biomarker for"| NFL["NFL"] TAU

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Wiki Tauopathies rel 18.10

tau (t-tau), phosphorylated tau (p-tau), and tau oligomers

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Wiki Tau Network Propagation Hypothesis (Prion-Like Spread) rel 17.90

Tau Propagation ### Prion-Like Properties of Pathological Tau Pathological tau

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Wiki Tau Propagation Mechanisms rel 17.30

Tau Protein Biology ### Normal Tau Function Tau is a microtubule

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Wiki Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP) rel 17.10

Tau PET (flortaucipir)](#tau-pet--flortaucipir) | 10 | Tau burden pattern

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Wiki nct02605785-tau-pet-psp rel 17.00

tau | 3R/4R | Research | #### 4R-Tau Selective Tracers Traditional tau PET tracers

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Wiki Tau Strain Diversity and Conformational Templating in Tauopathies rel 16.50

Tau protein](/proteins/tau) - [alpha-synuclein](/proteins/alpha-synuclein) - [Tau Phosphorylation](/mechanisms/tau-phosphorylation) - [Tau

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Wiki Total Tau (t-Tau) - Biomarker rel 16.30

TAU["TAU"] -->|"biomarker for"| GFAP["GFAP"] TAU["TAU"] -->|"biomarker for"| NFL["NFL"] TAU

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Wiki AAIC 2026: Tau Immunotherapy rel 16.00

tau_immunothe["AAIC 2026: Tau Immunotherapy"] style events_aaic_2026_tau

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Wiki Braak Staging and Tau Propagation Pathway rel 15.80

Tau"] -->|"Hyperphosphorylation"| B["p-Tau"] B -->|"Detachment"| C["Tau Oligomers

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Wiki Tau Pathology Pathway rel 15.70

tau an attractive therapeutic target[@arriagada1995]. ## Tau Biology ### Normal Tau

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Wiki PI-2620 Tau PET in PSP rel 15.50

tau antibodies binding to extracellular tau - Tau aggregation inhibitors - Tau

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Wiki Tau Pathology rel 15.40

Tau aggregation - Tau phosphorylation - Tau clearance via immunotherapy - Tau production

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Wiki Phosphorylated Tau 181 (p-tau 181) rel 15.10

Tau (p-tau 181, p-tau 217, tau PET) - **(N)**: Neurodegeneration

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Wiki Neurofibrillary Tangles rel 15.00

TAU protein ``` ## Tau Protein Biology ### Normal Tau Function Tau is a microtubule

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Wiki Tau Seeding and Propagation Pathway rel 15.00

tau isoforms with either three (3R tau) or four (4R tau

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Wiki tau-hyperphosphorylation rel 14.90

tau pathology include: - **Total tau (t-tau)**: Reflects neuronal damage

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Wiki Tau Pathology Pathway in Frontotemporal Dementia rel 14.70

tau pathology - **[MAPT Gene](/genes/mapt)** — Tau mutations causing FTD - **[Tau

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Wiki Neurofibrillary Tangle Propagation in Alzheimer's Disease rel 14.70

Tau Pathology Tau pathology forms one of the two hallmark

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Wiki Tau Immunotherapy Mechanisms rel 14.60

Tau["Tau"] -->|"interacts with"| MAPT["MAPT"] Tau["Tau"] -->|"associated with

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Wiki 4R Tau in Corticobasal Degeneration rel 14.50

tau](/proteins/tau-protein) and phosphorylated [tau](/proteins/tau-protein) (p-[tau](/proteins/tau-protein)181, p-[tau

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Wiki TPIRC - Tau Pathology and Immunotherapy Research Center rel 14.50

tau ### Normal Tau Post-Translational Modifications Beyond phosphorylation, tau undergoes

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Wiki p-tau rel 14.40

TAU["P-TAU"] TAU["TAU"] -->|"phosphorylates"| P_TAU["P-TAU

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Wiki Tau Propagation Hypothesis (Prion-Like Spread) rel 14.30

tau**: Predominantly 4R tau, straight filaments - **CBD tau**: Predominantly 4R tau

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Wiki Tauopathy rel 14.20

TAU["TAU"] TAU -->|"activates"| Tauopathy NEURODEGENERATION -->|"associated with"| Tauopathy ALZHEIMER

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Wiki First-in-Human 4R Tau Ligand Study in PSP (NCT07348276) rel 14.00

tau filaments | 4R tau filaments | | **Selectivity** | 4R > 3R tau | 4R > 3R tau

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Wiki MAPT→Tau→Aggregation→PSP Causal Chain rel 13.70

Tau ### Tau Biology **Tau** is a **intrinsically disordered protein** that

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Wiki apn-1607-tau-pet-phase3-nct07422857 rel 13.50

tau deposition - **Frontotemporal Dementia with Tau Pathology (FTD-tau)**: Various

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