Details

scope
mouse M1 cortex; Patch-seq
claim_text
Scala et al. (2021) identified a transcriptomically isolated Vip Lamp5 Lhx6 t-type that corresponds morphologically to deep L5/L6 neurogliaform cells (NGCs), an exception to the typical upper-layer Vip distribution.
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-02-classification
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
One interesting case was the transcriptomically isolated Vip Lamp5 Lhx6 type, which consists of deep L5/L6 neurogliaform cells (NGCs).
study_system
mouse M1 cortex; Patch-seq
section_title
Molecular Identity and Transcriptomic Taxonomy
evidence_summary
Patch-seq mapping: Vip Lamp5 Lhx6 t-type localizes to deep cortical layers and morphology matches NGC; conflicts with simple 'Vip = upper layer bipolar' rule.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
single_study
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-02-classification
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/s41586-020-2907-3",
  "claim": "Scala et al. (2021) identified a transcriptomically isolated Vip Lamp5 Lhx6 t-type that corresponds morphologically to deep L5/L6 neurogliaform cells (NGCs), an exception to the typical upper-layer Vip distribution.",
  "title": null,
  "cite_key": "Scala2021",
  "evidence": "Patch-seq mapping: Vip Lamp5 Lhx6 t-type localizes to deep cortical layers and morphology matches NGC; conflicts with simple 'Vip = upper layer bipolar' rule.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse M1 cortex; Patch-seq",
  "target_section": "section_02",
  "_source_cluster": "cluster_01_molecular_taxonomy",
  "replication_status": "single_study",
  "_source_cluster_index": 35,
  "claim_source_sentence": "One interesting case was the transcriptomically isolated Vip Lamp5 Lhx6 type, which consists of deep L5/L6 neurogliaform cells (NGCs)."
}
source_refs
[
  "paper:paper-be132b319290"
]
evidence_refs
[
  {
    "ref": "paper:paper-be132b319290"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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