Details

scope
mammal ACx
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-07-disinhibition-framework
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mammal ACx
section_title
Local Circuit Motifs and the Disinhibition Framework
evidence_summary
Inhibitory circuit gating of auditory critical-period plasticity
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-07-disinhibition-framework
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
The VIP-expressing 5-HT 3A R cell subtype does not regulate critical period plasticity A subtype of 5-HT 3A R interneuron that selectively expresses vasoactive intestinal peptide (VIP) sends descending axons to deeper cortical layers and disinhibits pyramidal cells 12 – 16 .
raw_fields
{
  "n": null,
  "doi": "10.1038/s41593-017-0064-2",
  "year": "2018",
  "claim": "The VIP-expressing 5-HT 3A R cell subtype does not regulate critical period plasticity A subtype of 5-HT 3A R interneuron that selectively expresses vasoactive intestinal peptide (VIP) sends descending axons to deeper cortical layers and disinhibits pyramidal cells 12 – 16 .",
  "title": null,
  "journal": "Nature neuroscience",
  "cite_key": "Takesian2018",
  "evidence": "Inhibitory circuit gating of auditory critical-period plasticity",
  "effect_size": null,
  "text_access": "fulltext",
  "first_author": "Takesian",
  "study_system": "mammal ACx",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Takesian, Bogart, Lichtman",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 23,
  "claim_source_sentence": "The VIP-expressing 5-HT 3A R cell subtype does not regulate critical period plasticity A subtype of 5-HT 3A R interneuron that selectively expresses vasoactive intestinal peptide (VIP) sends descending axons to deeper cortical layers and disinhibits pyramidal cells 12 – 16 .",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Notably, thalamocortical maps in L1 are themselves stable, serving as a scaffold for cortical plasticity throughout life."
}
source_refs
[
  "paper:paper-da0cfdd6fe54"
]
source_span
The VIP-expressing 5-HT 3A R cell subtype does not regulate critical period plasticity A subtype of 5-HT 3A R interneuron that selectively expresses vasoactive intestinal peptide (VIP) sends descending axons to deeper cortical layers and disinhibits pyramidal cells 12 – 16 .
evidence_refs
[
  {
    "ref": "paper:paper-da0cfdd6fe54"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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