Details

scope
mammal neocortex
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
effect_size
0.5 ms
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-07-disinhibition-framework
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mammal neocortex
section_title
Local Circuit Motifs and the Disinhibition Framework
evidence_summary
Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-07-disinhibition-framework
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.
raw_fields
{
  "n": 10,
  "doi": "10.1016/j.neuron.2018.09.001",
  "year": "2018",
  "claim": "In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.",
  "title": null,
  "journal": "Neuron",
  "cite_key": "Abs2018",
  "evidence": "Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons",
  "effect_size": "0.5 ms",
  "text_access": "fulltext",
  "first_author": "Abs",
  "study_system": "mammal neocortex",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Abs, Poorthuis, Apelblat",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 14,
  "claim_source_sentence": "In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The chosen irradiance (gray lines, 45 mW/mm 2 ) elicited 1.2 action potentials per pulse (0.5 ms, n = 10). (C) Average IPSCs in ChR-2 negative L1 INs (gray, n = 12), L2/3 PNs (black, n = 24), and L2/3 INs (red, n = 11). (D) Comparison of L1 NDNF-IN-mediated IPSCs in the different postsynaptic populations."
}
source_refs
[
  "paper:paper-cddfd665bb4c"
]
source_span
In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.
evidence_refs
[
  {
    "ref": "paper:paper-cddfd665bb4c"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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